Jezzard P, Song A W
Unit on MRI Physics, LPP/NIMH, National Institutes of Health, Bethesda, Maryland 20892-1366, USA.
Neuroimage. 1996 Dec;4(3 Pt 3):S63-75. doi: 10.1006/nimg.1996.0056.
Magnetic resonance imaging (MRI) has become an established and invaluable tool in the diagnosis of numerous diseases through its ability to show pathologic contrast in images of soft tissue. More recently, MRI has found application in the study of organ function, principally in the brain and heart. This article deals with MRI imaging of brain function and describes some of the techniques that allow physiological parameters such as cerebral blood volume, cerebral blood oxygenation, and cerebral perfusion to be determined. Additionally, some of the potentially confounding influences in these experiments are discussed.
磁共振成像（MRI）凭借其在软组织图像中显示病理对比度的能力，已成为诊断多种疾病的既定且极为重要的工具。最近，MRI在器官功能研究中得到了应用，主要是在大脑和心脏方面。本文论述了脑功能的MRI成像，并描述了一些能够测定诸如脑血容量、脑血氧合和脑灌注等生理参数的技术。此外，还讨论了这些实验中一些可能产生混淆的影响因素。
