巴尤病毒（布尼亚病毒科：汉坦病毒）的分离、遗传多样性及地理分布

Isolation, genetic diversity, and geographic distribution of Bayou virus (Bunyaviridae: hantavirus).

作者信息

Ksiazek T G, Nichol S T, Mills J N, Groves M G, Wozniak A, McAdams S, Monroe M C, Johnson A M, Martin M L, Peters C J, Rollin P E

机构信息

Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.

出版信息

Am J Trop Med Hyg. 1997 Oct;57(4):445-8. doi: 10.4269/ajtmh.1997.57.445.

DOI:10.4269/ajtmh.1997.57.445

PMID:9347961

Abstract

Bayou hantavirus, previously implicated in human hantavirus pulmonary syndrome in Louisiana, was isolated from a rice rat (Oryzomys palustris) captured in Georgia. The presence of antibody among rice rats captured throughout the southeastern United States and the extent of diversity among the genetic variants of Bayou viruses suggest that the rice rat is the most likely natural reservoir of the virus and that both virus and host have probably co-evolved for some years.

摘要

先前在路易斯安那州人类汉坦病毒肺综合征中被牵连的河口汉坦病毒，是从在佐治亚州捕获的一只稻鼠（沼泽稻鼠）中分离出来的。在美国东南部各地捕获的稻鼠中存在抗体，以及河口病毒基因变体之间的多样性程度表明，稻鼠是该病毒最有可能的天然宿主，并且病毒和宿主可能已经共同进化了数年。