Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Emerg Infect Dis. 2011 Jul;17(7):1195-201. doi: 10.3201/eid1707.101306.
Hantavirus pulmonary syndrome (HPS) is a severe respiratory illness identified in 1993. Since its identification, the Centers for Disease Control and Prevention has obtained standardized information about and maintained a registry of all laboratory-confirmed HPS cases in the United States. During 1993-2009, a total of 510 HPS cases were identified. Case counts have varied from 11 to 48 per year (case-fatality rate 35%). However, there were no trends suggesting increasing or decreasing case counts or fatality rates. Although cases were reported in 30 states, most cases occurred in the western half of the country; annual case counts varied most in the southwestern United States. Increased hematocrits, leukocyte counts, and creatinine levels were more common in HPS case-patients who died. HPS is a severe disease with a high case-fatality rate, and cases continue to occur. The greatest potential for high annual HPS incidence exists in the southwestern United States.
汉坦病毒肺综合征（HPS）是一种严重的呼吸道疾病，于 1993 年被确认。自其被确认以来，疾病控制与预防中心已经获得了美国所有实验室确诊的 HPS 病例的标准化信息，并维护了一个登记处。在 1993 年至 2009 年期间，共发现了 510 例 HPS 病例。病例数每年从 11 例到 48 例不等（病死率为 35%）。然而，并没有趋势表明病例数或病死率呈上升或下降趋势。尽管报告了 30 个州的病例，但大多数病例发生在美国西部；美国西南部的年度病例数差异最大。死亡的 HPS 病例患者中，血细胞比容、白细胞计数和肌酐水平升高更为常见。HPS 是一种严重疾病，病死率高，病例仍在发生。美国西南部发生高年度 HPS 发病率的潜力最大。
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