Seto F
Poult Sci. 1976 Jan;55(1):172-9. doi: 10.3382/ps.0550172.
Two- and three-week old chicks that received at hatching serum from either unimmunized birds or from chickens immunized with bovine serum albumin responded with normal hemagglutinin titers to immunization with mouse erythrocytes (MRBC). Other chicks administered at hatching or as embryos with homologous serum high in anti-MRBC activity responded poorly to MRBC immunization. When donor serum samples collected on different days after immunization were tested, the immunosuppressive capacity was negligible the first two days, increased in potency thereafter to a maximum level by the end of the week. The increase with time in the inhibiting property of the donor serum paralleled the serum anti-MRBC hemagglutinin response profile. The immune capacity of the antibody-treated recipients was severely depressed for over two weeks. By the fourth week, however, the immune responsiveness to MRBC, as measured by serum hemagglutinin titers and production of antigen sensitive units, had recovered to near normal levels.
在孵化时接受来自未免疫禽类或用牛血清白蛋白免疫的鸡的血清的2周龄和3周龄雏鸡，对用小鼠红细胞（MRBC）进行免疫反应时，血凝素滴度正常。其他在孵化时或作为胚胎接受具有高抗MRBC活性的同源血清的雏鸡，对MRBC免疫反应不佳。当检测免疫后不同天数收集的供体血清样本时，免疫抑制能力在前两天可忽略不计，此后效力增加，到周末达到最高水平。供体血清抑制特性随时间的增加与血清抗MRBC血凝素反应曲线平行。抗体处理的受体的免疫能力在两周多的时间里严重受到抑制。然而，到第四周，通过血清血凝素滴度和抗原敏感单位的产生来衡量，对MRBC的免疫反应性已恢复到接近正常水平。
