Gorinstein S, Zemser M, Berliner M, Goldstein R, Libman I, Trakhtenberg S, Caspi A
School of Pharmacy, Hebrew University of Jerusalem, Israel.
J Intern Med. 1997 Sep;242(3):219-24. doi: 10.1046/j.1365-2796.1997.00195.x.
The aim of this study was to evaluate the influence of moderate beer consumption on lipid metabolism and antioxidant activity in patients (pts) with coronary artery disease (CAD).
Forty-eight male pts with CAD not alcohol beverages consumers were randomly divided into experimental (EG) and control (CG) groups, 24 pts each.
Rehovot University Hospital, Israel.
Every patient of the EG during a period of 30 consecutive days consumed 330 ml of Maccabee beer (> 20 g of alcohol). The pts of the CG did not consume alcohol during the trial period.
A wide range of tests including total cholesterol, LDL-C, HDL-C, total tocopherol and alpha-tocopherol.
Only in the pts of the EG were found a tendency to an increase of the level of HDL-C and a statistically significant rise in the level of total tocopherol (P < 0.025) and alpha-tocopherol (P < 0.025).
Even a short period of moderate beer consumption leads to some favourable biochemical changes in blood of pts with CAD which are widely regarded as indicators of CAD prevention.
本研究旨在评估适量饮用啤酒对冠心病(CAD)患者脂质代谢和抗氧化活性的影响。
48名不饮用酒精饮料的男性CAD患者被随机分为实验组(EG)和对照组(CG),每组24名患者。
以色列雷霍沃特大学医院。
实验组的每位患者在连续30天内饮用330毫升马卡比啤酒(酒精含量>20克)。对照组患者在试验期间不饮酒。
进行了一系列测试,包括总胆固醇、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、总生育酚和α-生育酚。
仅在实验组患者中发现高密度脂蛋白胆固醇水平有升高趋势,且总生育酚水平(P<0.025)和α-生育酚水平(P<0.025)有统计学显著升高。
即使是短时间适量饮用啤酒,也会使CAD患者血液发生一些有益的生化变化,这些变化被广泛视为预防CAD的指标。