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喉基底样鳞状细胞癌:1例报告

Basaloid squamous carcinoma of the larynx: report of a case.

作者信息

Sato M, Horiuchi M, Ogata T, Yamazaki M, Sakai M, Kato Y, Shimamura K

机构信息

Department of Otorhinolaryngology, Tokai University Tokyo Hospital, Japan.

出版信息

Auris Nasus Larynx. 1997 Oct;24(4):417-22. doi: 10.1016/s0385-8146(97)10005-0.

Abstract

Basaloid squamous carcinoma (BSC) is a rare neoplasm. We present a case of basaloid squamous carcinoma of the larynx in a 57-year-old male patient. The diagnosis before treatment was supraglottic carcinoma (T3N1MO) and biopsy of the larynx revealed a poorly differentiated squamous cell carcinoma. Total laryngectomy and right radical neck dissection were performed, and pathological studies of a specimen removed from the larynx revealed BSC of the larynx. The patient's postoperative progress was uneventful, however, 12 months later he developed lung metastasis of the left side. The patient underwent partial resection of the lung. He developed recurrence of lung metastasis 6 months later. Chemotherapy with cisplatin (CDDP) and vindesine sulfate (VSD) was administered in two courses, but the efficacy was evaluated as no change (NC). At present, 26 months after the first visit, he has been asymptomatic with lung metastasis, and there was no evidence of recurrence in the neck.

摘要

基底样鳞状细胞癌(BSC)是一种罕见的肿瘤。我们报告一例57岁男性患者的喉基底样鳞状细胞癌。治疗前诊断为声门上癌(T3N1M0),喉部活检显示为低分化鳞状细胞癌。行全喉切除术及右侧根治性颈清扫术,对切除的喉部标本进行病理研究显示为喉基底样鳞状细胞癌。患者术后恢复顺利,然而,12个月后出现左侧肺转移。患者接受了肺部分切除术。6个月后出现肺转移复发。给予顺铂(CDDP)和硫酸长春地辛(VSD)化疗两个疗程,但疗效评估为病情无变化(NC)。目前,首次就诊26个月后,他的肺转移无症状,颈部无复发迹象。

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