Ahmed S K, Thomson H J
University of Birmingham, UK.
J R Coll Surg Edinb. 1997 Oct;42(5):331-3.
With the objective of exploring the association between breakfast and minor anal complaints, an age, sex and pregnancy matched case-control study was carried out in the out-patient clinics at Birmingham Heartlands Hospital. Patients were selected after personal interviews using a structured questionnaire in out-patient clinics. Information on age, sex, occupation and breakfast habits, as well as on haemorrhoids and anal fissure, was obtained. Patients who had haemorrhoids or anal fissure were placed in the case group; the remainder were controls. Any patient with diverticulosis, inflammatory bowel disease, colon cancer or bowel resection for any reason was excluded from the study. The main outcome measures were the odds of developing haemorrhoids or fissure in patients who did not eat breakfast. The results are based on 47 cases that were age, sex and pregnancy matched. Of the case group, 36% did not eat breakfast, compared with 11% in the control group. The analysis demonstrated a 7.5-fold increase in the odds of suffering from haemorrhoids or anal fissures in matched subjects who did not eat breakfast, with a very high level of significance (P = 0.0036). This indicates that there is a very strong association between failure to eat breakfast and haemorrhoids or anal fissure. It is anticipated that educating the public to eat breakfast would lead to a long-term fall in the incidence of anal complaints, in the attendant morbidity for the patients and in the cost to the health service.
为了探究早餐与轻微肛门疾病之间的关联，在伯明翰心脏地带医院的门诊开展了一项年龄、性别和妊娠情况相匹配的病例对照研究。在门诊通过结构化问卷进行个人访谈后选取患者。获取了有关年龄、性别、职业和早餐习惯以及痔疮和肛裂的信息。患有痔疮或肛裂的患者被纳入病例组；其余患者为对照组。任何患有憩室病、炎症性肠病、结肠癌或因任何原因接受过肠道切除术的患者均被排除在研究之外。主要观察指标是不吃早餐的患者患痔疮或肛裂的几率。结果基于47例年龄、性别和妊娠情况相匹配的病例。病例组中，36%的患者不吃早餐，而对照组这一比例为11%。分析表明，不吃早餐的匹配受试者患痔疮或肛裂的几率增加了7.5倍，具有非常高的显著性水平（P = 0.0036）。这表明不吃早餐与痔疮或肛裂之间存在非常强的关联。预计对公众进行吃早餐的教育将导致肛门疾病发病率的长期下降，患者随之而来的发病率降低以及医疗服务成本降低。
