Patten S B, Williams J V, Haynes L, McCruden J, Arboleda-Flórez J
Alberta Heritage Foundation for Medical Research, Calgary.
Can J Psychiatry. 1997 Oct;42(8):858-63. doi: 10.1177/070674379704200809.
To estimate prospectively the incidence of delirium in psychiatric inpatients and to identify risk factors for delirium in this population.
The subjects were nondelirious patients newly admitted to the Calgary General Hospital. The Delirium Symptom Interview (DSI), the Confusion Assessment Method (CAM), and the Mini-Mental State Examination (MMSE) were used to identify incident cases of delirium. In order to evaluate the potential impact of selection bias, we conducted a supplementary analysis using record linkage to an electronic administrative data base with coverage of the target population.
Of 420 admissions to the hospital, 401 subjects provided informed consent and were not delirious at the time of admission. There were 9 incident cases of delirium. The cumulative incidence rate was, therefore, 2.14 per 100 admissions. The record linkage analysis did not uncover evidence of selection bias. Delirium was associated with a significantly increased length of stay in hospital.
Delirium is an uncommon incident event in the psychiatric inpatient population. The incidence rate reported here may be useful as a benchmark for the identification of excessive rates in other inpatient settings. Since delirium is sometimes related to modifiable therapeutic factors, an excessive rate should prompt a search for its causes.
前瞻性评估精神科住院患者谵妄的发生率，并确定该人群中谵妄的危险因素。
研究对象为新入住卡尔加里综合医院的非谵妄患者。采用谵妄症状访谈（DSI）、混乱评估方法（CAM）和简易精神状态检查表（MMSE）来识别谵妄的发病病例。为了评估选择偏倚的潜在影响，我们使用与覆盖目标人群的电子管理数据库进行记录链接的方式进行了补充分析。
在420例入院患者中，401名受试者提供了知情同意书，且入院时无谵妄症状。有9例谵妄发病病例。因此，累积发病率为每100例入院患者中有2.14例。记录链接分析未发现选择偏倚的证据。谵妄与住院时间显著延长有关。
谵妄在精神科住院患者中是一种不常见的发病事件。此处报告的发病率可作为识别其他住院环境中过高发病率的基准。由于谵妄有时与可改变的治疗因素有关，过高的发病率应促使人们寻找其原因。
