Diez M, Hornick J L, Baldwin P, Istasse L
Faculty of Veterinary Medicine, University of Liege, Belgium.
Am J Vet Res. 1997 Nov;58(11):1238-42.
To evaluate effects of a blend of fructo-oligosaccharides and sugar beet fiber (4:1) at 3 incorporation rates on nutrient digestibility and plasma glucose, insulin, alpha-aminonitrogen, urea, cholesterol, and triglycerides concentrations measured weekly in nonfed dogs and during a 360-minute period after a meal.
8 castrated 1- to 1.4-year-old young adult male Beagles weighing 10.0 to 13.5 kg.
Diets containing 2 incorporation rates of a blend of fructo-oligosaccharides and sugar beet fiber (5 and 10% on a dry matter basis [diets B and C, respectively]) were compared with a control diet without additional fiber (diet A). The 3 diets were evaluated for ability to modify digestibility of dry and organic matter, protein, fat, and ash and for effects on plasma glucose, insulin, alpha-aminonitrogen, urea, cholesterol, and triglycerides concentrations. Each diet was fed for 6 weeks; plasma samples were collected weekly before feeding and after feeding on the last day of the period. During 1 week at the end of the 6-week period, dogs were kept in metabolic cages. Each period of the block was followed by a 4-week washout period.
Incorporating the blend of fructo-oligosaccharides and sugar beet fiber in the diet was associated with greater passage of wet feces (diets B and C) and lower protein digestibility (diet C). Postprandial glucose (diet C), urea (diets B and C) and triglyceride (diets B and C) concentrations were significantly (P < 0.01) decreased. Weekly preprandial measurements were characterized by decreased urea (diets B and C), cholesterol (diet C), and triglycerides (diets B and C) concentrations (P < 0.001).
Chronic consumption of fermentable fiber is associated with mildly decreased protein digestibility and with metabolic effects in nonfed or fed dogs.
A blend of fructo-oligosaccharides and sugar beet fiber should be tested as a dietary aid for treatment of chronic diseases, such as diabetes mellitus or hyperlipidemia, in dogs.
评估低聚果糖和甜菜纤维混合物（4:1）在3种添加比例下，对非喂食状态下的犬以及进食后360分钟内每周测量的营养物质消化率和血浆葡萄糖、胰岛素、α-氨基氮、尿素、胆固醇及甘油三酯浓度的影响。
8只1至1.4岁的去势年轻成年雄性比格犬，体重10.0至13.5千克。
将含有2种低聚果糖和甜菜纤维混合物添加比例（分别以干物质计为5%和10%，即饮食B和饮食C）的日粮与无额外纤维的对照日粮（饮食A）进行比较。评估这3种日粮对干物质、有机物、蛋白质、脂肪和灰分消化率的改善能力，以及对血浆葡萄糖、胰岛素、α-氨基氮、尿素、胆固醇和甘油三酯浓度的影响。每种日粮喂养6周；在该时间段最后一天喂食前和喂食后每周采集血浆样本。在6周时间段结束时的1周内，将犬置于代谢笼中。每个实验阶段之后有4周的洗脱期。
日粮中添加低聚果糖和甜菜纤维混合物与湿粪排出量增加（饮食B和饮食C）以及蛋白质消化率降低（饮食C）有关。餐后葡萄糖（饮食C）、尿素（饮食B和饮食C）和甘油三酯（饮食B和饮食C）浓度显著降低（P < 0.01）。每周餐前测量结果显示，尿素（饮食B和饮食C）、胆固醇（饮食C）和甘油三酯（饮食B和饮食C）浓度降低（P < 0.001）。
长期食用可发酵纤维与非喂食或喂食状态下的犬蛋白质消化率轻度降低及代谢效应有关。
低聚果糖和甜菜纤维混合物应作为犬类慢性疾病（如糖尿病或高脂血症）治疗的膳食辅助剂进行测试。
