Golding J, Emmett P M, Rogers I S
Unit of Pediatric and Perinatal Epidemiology, University of Bristol, UK.
Early Hum Dev. 1997 Oct 29;49 Suppl:S131-42. doi: 10.1016/s0378-3782(97)00059-5.
Feeding of breast milk in the first weeks of life appears to have a strong protective effect against necrotising enterocolitis. Nevertheless breast milk also seems to be positively linked to the development of jaundice and to late haemorrhagic disease in infants who have not received vitamin K supplements. There is no consistent evidence that other childhood conditions such as insulin dependent diabetes or cancer are less prevalent among children who have been breast fed. Among adult conditions suggested to be less prevalent in the breast fed, only single reports of significant findings for multiple sclerosis and breast cancer exist and convincing corroboration is not available. There are a number of studies that indicate a relationship between breast feeding and later cholesterol levels--and one that has considered the mortality of ischaemic heart disease among adult males. There is some suggestion that breast feeding (during the first year of life) is the optimal protection against future raised lipid levels and mortality from coronary heart disease, but the evidence is far from conclusive. The major health advantage of breast feeding that has been clearly demonstrated remains in the protection of the infant from certain infections in early life. If there are other long-term health advantages they have yet to be fully elucidated and confirmed.
在生命的最初几周进行母乳喂养似乎对坏死性小肠结肠炎具有很强的保护作用。然而,母乳似乎也与黄疸的发生以及未补充维生素K的婴儿的晚发性出血性疾病呈正相关。没有一致的证据表明,在接受母乳喂养的儿童中,其他儿童疾病如胰岛素依赖型糖尿病或癌症的发病率较低。在成人疾病中,有报道称母乳喂养的人群中多发性硬化症和乳腺癌的发病率较低,但缺乏令人信服的确证。有多项研究表明母乳喂养与后期胆固醇水平之间存在关联,还有一项研究考虑了成年男性缺血性心脏病的死亡率。有迹象表明,母乳喂养(在生命的第一年)是预防未来血脂升高和冠心病死亡的最佳保护措施,但证据远非确凿。母乳喂养已明确证明的主要健康益处仍然是保护婴儿在生命早期免受某些感染。如果还有其他长期健康益处,它们尚未得到充分阐明和证实。