作为一种进化范式的传染病
Infectious disease as an evolutionary paradigm.
作者信息
Lederberg J
机构信息
Sackler Foundation Scholar, Rockefeller University, New York, New York 10021-6399, USA.
出版信息
Emerg Infect Dis. 1997 Oct-Dec;3(4):417-23. doi: 10.3201/eid0304.970402.
Abstract
The basic principles of genetics and evolution apply equally to human hosts and to emerging infections, in which foodborne outbreaks play an important and growing role. However, we are dealing with a very complicated coevolutionary process in which infectious agent outcomes range from mutual annihilation to mutual integration and resynthesis of a new species. In our race against microbial evolution, new molecular biology tools will help us study the past; education and a global public health perspective will help us deal better with the future.
摘要
遗传学和进化的基本原理同样适用于人类宿主和新出现的感染，其中食源性疾病暴发起着重要且日益重要的作用。然而，我们正在应对一个非常复杂的共同进化过程，在这个过程中，病原体的结果从相互毁灭到相互整合以及新物种的重新合成不等。在我们与微生物进化的竞赛中，新的分子生物学工具将帮助我们研究过去；教育和全球公共卫生视角将帮助我们更好地应对未来。
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