费尔蒂综合征。锂对粒细胞生成的影响。
Felty's syndrome. Effect of lithium on granulopoiesis.
作者信息
Gupta R C, Robinson W A, Kurnick J E
出版信息
Am J Med. 1976 Jul;61(1):29-32. doi: 10.1016/0002-9343(76)90027-9.
PMID:937368
Abstract
The effect of lithium carbonate upon granulopoiesis was studied in eight patients with Felty's syndrome. Absolute granulocyte counts increased in all patients receiving 900 mg lithium carbonate daily for six weeks. Increased urinary and serum granulocyte colony-stimulating activity was observed in all patients during lithium therapy. A casual relationship between increases in colony-stimulating activity and increased granulocytes is postulated.
摘要
在8例费尔蒂综合征患者中研究了碳酸锂对粒细胞生成的影响。所有接受每日900毫克碳酸锂治疗六周的患者，其绝对粒细胞计数均增加。在锂治疗期间，所有患者的尿和血清粒细胞集落刺激活性均增加。推测集落刺激活性增加与粒细胞增加之间存在因果关系。
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