Sartucci F, Bonfiglio L, Del Seppia C, Luschi P, Ghione S, Murri L, Papi F
Department of Neurosciences, University of Pisa, Italy.
Brain Res. 1997 Sep 26;769(2):362-6. doi: 10.1016/s0006-8993(97)00755-5.
Nociception has been reported to be influenced by exposure to magnetic fields (MFs). The aim of this study was to investigate the effects of 2 h exposure to weak, oscillating MFs on pain perception thresholds and on pain-related somatosensory evoked potentials (SEPs). In 11 healthy volunteers, pain perception thresholds and pain-related SEPs were assessed by intracutaneous electrical stimulation. After sham treatment, pain thresholds significantly increased, whereas after MFs a slight non-significant decrease in thresholds was found. After both treatments pain-related SEP amplitude was reduced, but this decrease was more evident and statistically significant only after MF exposure. The increase found in thresholds after sham exposure may be due to stress-induced analgesia (SIA) and the contrasting behaviour recorded after MF exposure might indicate a suppression of SIA. The significant reduction in pain-related SEP amplitude observed after MF exposure provides the first evidence that human SEPs are influenced by MFs.
据报道，伤害感受会受到暴露于磁场（MFs）的影响。本研究的目的是调查暴露于微弱振荡磁场2小时对疼痛感知阈值以及与疼痛相关的体感诱发电位（SEPs）的影响。在11名健康志愿者中，通过皮内电刺激评估疼痛感知阈值和与疼痛相关的SEPs。假治疗后，疼痛阈值显著增加，而在磁场暴露后，发现阈值有轻微但不显著的下降。两种治疗后，与疼痛相关的SEP波幅均降低，但这种降低仅在磁场暴露后更为明显且具有统计学意义。假暴露后阈值的增加可能是由于应激诱导的镇痛（SIA），而磁场暴露后记录到的相反行为可能表明SIA受到抑制。磁场暴露后观察到的与疼痛相关的SEP波幅显著降低提供了人类SEPs受磁场影响的首个证据。
