Herschler J
Am J Ophthalmol. 1976 Jul;82(1):90-3. doi: 10.1016/0002-9394(76)90669-3.
Twelve patients (14 eyes) had intraocular pressure elevations induced by repository coritcosteroids. The duration and severity of the resulting pressure elevations were directly related to the decreasing solubility of the agent employed. Ten patitens had received intensive topical corticosteroids before injection, resulting in no intraocular pressure elevations during that period. Two patients who developed marked intraocular pressure elevations after repository corticosteroid injection did not manifest a positive response on subsequent topical corticosteroid testing.
12名患者(14只眼)出现了长效皮质类固醇引起的眼压升高。由此导致的眼压升高的持续时间和严重程度与所用药物溶解度的降低直接相关。10名患者在注射前接受了强化局部皮质类固醇治疗,在此期间未出现眼压升高。2名患者在长效皮质类固醇注射后出现明显的眼压升高,在随后的局部皮质类固醇测试中未表现出阳性反应。