Andersson L
Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden.
J Hered. 1997 Sep-Oct;88(5):380-3. doi: 10.1093/oxfordjournals.jhered.a023122.
Intercrosses between divergent lines of domestic animals adapted to different environmental conditions and/or production systems provide unique opportunities for mapping phenotypic trait loci. The strategy resembles the use of interspecific crosses developed for general linkage mapping. We have made an intercross between the wild pig and domestic pigs of the Large White breed. A comprehensive linkage map comprising more than 230 genetic markers has been established. The successful use of this intercross for mapping loci for some monogenic traits (coat color and an intestinal receptor for E. coli K88 pili) as well as quantitative trait loci (QTLs) with major effects of growth and fatness is reviewed.
将适应不同环境条件和/或生产系统的家畜不同品系进行杂交，为绘制表型性状基因座提供了独特的机会。该策略类似于为一般连锁图谱绘制而开发的种间杂交的应用。我们已将野猪与大白品种的家猪进行了杂交。现已构建了一个包含230多个遗传标记的综合连锁图谱。本文综述了利用这种杂交来定位一些单基因性状（毛色和大肠杆菌K88菌毛的肠道受体）的基因座以及对生长和脂肪含量有主要影响的数量性状基因座（QTL）的成功案例。
