Grace R R, Jordan P H
Ann Surg. 1976 Jul;184(1):16-21. doi: 10.1097/00000658-197607000-00002.
The treatment of 54 patients with pancreatic pseudocysts was reviewed. The operative mortality was 11% and after an average followup of 3 years the recurrence rate was 3.8%. Hemorrhage was the most significant complication of pseudocysts and occurred in 4 patients preoperatively and three patients postoperatively. The patients who developed recurrence or died had been operated within one day after the diagnoses of pseudocysts were made. The deaths were due to the conditions that necessitated the emergency operations rather than to the fact that the cyst wall had not adequately matured. Ideally, operation should be performed when the patient has reached an optimal clinical condition and the walls of the cyst are sufficiently thick. Currently there is no guide for estimation of the state of cyst maturation, although this may develop with the use of ultrasound. Since complications can develop during a prolonged observation period it was our policy to proceed with surgery as soon after diagnosis as the patient was in satisfactory clinical condition. It is evident from this study that internal drainage can be performed safely in less time than the 6 weeks frequently recommended. Morbidity and mortality were not adversely affected by a short interval between diagnosis and operation if the timing was a matter of election rather than a condition of emergency.
对54例胰腺假性囊肿患者的治疗情况进行了回顾。手术死亡率为11%,平均随访3年后复发率为3.8%。出血是假性囊肿最严重的并发症,4例患者在术前发生出血,3例在术后发生出血。出现复发或死亡的患者是在诊断为假性囊肿后一天内接受手术的。死亡是由于需要进行急诊手术的病情,而非囊肿壁未充分成熟。理想情况下,应在患者达到最佳临床状态且囊肿壁足够厚时进行手术。目前尚无评估囊肿成熟状态的指南,不过这可能会随着超声检查的应用而得到发展。由于在延长的观察期内可能会出现并发症,我们的策略是在诊断后尽快对临床状态良好的患者进行手术。这项研究表明,内引流可以在比经常推荐的6周更短的时间内安全进行。如果手术时机是经过选择而非紧急情况,那么诊断与手术之间的间隔时间较短并不会对发病率和死亡率产生不利影响。