[中国云南瑞丽及其他县HIV-1 C亚型分布研究]

[Study on the distribution HIV-1 C subtype in Ruili and other counties, Yunnan, China].

作者信息

Li D Q, Zheng X W, Zhang G Y

机构信息

Center for AIDS Surveillance, Chinese Academy of Preventive Medicine, Beijing.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 1996 Dec;17(6):337-9.

PMID:9387597

Abstract

Cooperating with CDC, USA, the Center for AIDS Surveillance, Chinese Academy of Preventive Medicine, first identified the epidemic of HIV-1 C subtype virus in China in 1994. As part of the Eighth-Five National Scientific Program and to get information about the geographical distribution of C subtype of HIV-1 and its epidemic time span in Yunnan, using specific peptide ELISA, we tested 192 anti-HIV-1 positive serums, among intravenous drug users. The results indicated that C subtype of HIV-1 started to appear in Ruili (5.1%) in 1992, and the rates were 12.9% in Ruili and 30.4% in Longchuan in 1993, up to 31.9% in Ruili and 33.3% in Longchuan in 1994. The porpotion of C subtype is increasing among the drug users by year. Whether C subtype would become the main the main epidemic subtype in this areas remains to be under observation.

摘要

中国预防医学科学院艾滋病监测中心与美国疾病控制中心合作，于1994年首次在中国发现HIV-1 C亚型病毒的流行。作为“八五”国家科研项目的一部分，为了解HIV-1 C亚型在云南省的地理分布及其流行时间跨度，我们采用特异性肽ELISA法，对192份静脉吸毒者的抗HIV-1阳性血清进行了检测。结果显示，HIV-1 C亚型于1992年开始在瑞丽出现（5.1%），1993年在瑞丽的感染率为12.9%，陇川为30.4%，1994年在瑞丽升至31.9%，陇川为33.3%。吸毒者中C亚型的比例逐年上升。C亚型是否会成为该地区的主要流行亚型仍有待观察。