Yan Q, Sun Y, Lin J
China-Japan Friendship Hospital, Beijing.
Zhonghua Nei Ke Za Zhi. 1996 Apr;35(4):235-8.
To study quantitatively the effect of breathing exercises on the prevention of progression in chronic obstructive pulmonary disease (COPD), 324 patients with stable COPD were randomly assigned to either breathing exercises (BE) or placebo medicine as control. The maximum respiratory pressure (320 cases) and transdiaphragmatic pressure (129 cases) were monitored with RMS-1 and Type-2 gastrointestinal pressure measuring instrument. BE were taught and checked by experienced specialists periodically. Patients in BE group were compared with those in the control group by measuring MIP, MEP, Pdi, and Pdimax after one to 20 months. In BE group MIP increased by 30.42%, MEP 32.10%, Pdi 30.94%, and Pdimax 65.59% (P < 0.001). No significant change was observed in the control group. MIP, MEP, Pdi, and Pdimax increased by 6.95%, 2.92%, 14.63% and 9.05% respectively (P < 0.05) in the control group. It is shown preliminarily that BE had potent and lasting effect on respiratory muscle contraction after studying large number of cases. The methods mentioned above can be used as quantitative indices for the contractile properties of respiratory muscle.
为了定量研究呼吸锻炼对慢性阻塞性肺疾病(COPD)病情进展的预防作用,将324例稳定期COPD患者随机分为呼吸锻炼组(BE)和作为对照的安慰剂组。使用RMS - 1型和2型胃肠压力测量仪监测最大呼吸压力(320例)和跨膈压(129例)。由经验丰富的专家定期教授并检查呼吸锻炼。在1至20个月后,通过测量最大吸气压(MIP)、最大呼气压(MEP)、跨膈压(Pdi)和最大跨膈压(Pdimax),将呼吸锻炼组的患者与对照组的患者进行比较。呼吸锻炼组中,MIP增加了30.42%,MEP增加了32.10%,Pdi增加了30.94%,Pdimax增加了65.59%(P < 0.001)。对照组未观察到显著变化。对照组中,MIP、MEP、Pdi和Pdimax分别增加了6.95%、2.92%、14.63%和9.05%(P < 0.05)。大量病例研究初步表明,呼吸锻炼对呼吸肌收缩有强大而持久的作用。上述方法可作为呼吸肌收缩特性的定量指标。