O'Hare J A, Azher T
Department of Medicine, Limerick Regional General Hospital, Dooradoyle.
Ir J Med Sci. 1997 Oct-Dec;166(4):239-40. doi: 10.1007/BF02944242.
We report on a 25 yr old woman with primary autoimmune hyperthyroidism who was treated with carbimazole. Forty-three days later she developed agranulocytosis (64 x 10(6)/l). With 4 days treatment with recombinant human Granulocyte Colony Stimulating factor the granulocyte count rose to normal--4,350 cells x 10(6)/l. This is considerably faster than the rate of spontaneous recovery which usually takes one to 2 weeks.
我们报告了一名25岁患有原发性自身免疫性甲状腺功能亢进症的女性，她接受了卡比马唑治疗。43天后，她出现了粒细胞缺乏症（64×10⁶/L）。经过4天的重组人粒细胞集落刺激因子治疗，粒细胞计数恢复正常——4350个细胞×10⁶/L。这比通常需要1至2周的自发恢复速度要快得多。
