Gulumian M, Nkosibomvu Z L, Channa K, Pollak H
Biochemistry Research Section, National Centre for Occupational Health, Johannesburg, South Africa.
Environ Health Perspect. 1997 Sep;105 Suppl 5(Suppl 5):1041-4. doi: 10.1289/ehp.97105s51041.
Exposure of animals and humans to crocidolite asbestos fibers produces fibrosis and two types of cancers: bronchogenic carcinoma and mesothelioma. It is therefore desirable to reduce toxicity of these fibers without affecting their other characteristics. In this study, commercial crocidolite asbestos fibers were radiated with microwave radiation at different temperatures. Radiated fibers and nonradiated original fibers were then studied by Mössbauer spectroscopy to quantify the amount of ferric and ferrous ions present at structurally different sites in each crocidolite sample. They were also studied for their ability to initiate the peroxidation of linoleic acid to assess the effect of radiation on this process. Results showed that microwave radiation reduced the total Fe2+/Fe3+ ratio. This reduction produced a concomitant decrease in the ability of the radiated samples to peroxidize linoleic acid.
支气管癌和间皮瘤。因此,在不影响这些纤维其他特性的情况下降低其毒性是很有必要的。在本研究中,商用青石棉纤维在不同温度下接受微波辐射。然后通过穆斯堡尔光谱法研究辐射后的纤维和未辐射的原始纤维,以量化每个青石棉样品中结构不同位点上存在的三价铁离子和二价铁离子的量。还研究了它们引发亚油酸过氧化的能力,以评估辐射对该过程的影响。结果表明,微波辐射降低了总Fe2+/Fe3+比率。这种降低伴随着辐射样品使亚油酸过氧化能力的下降。