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Adenosine bronchoprovocation: a promising marker of allergic inflammation in asthma?腺苷支气管激发试验：哮喘中过敏性炎症的一个有前景的标志物？
Thorax. 1997 Oct;52(10):919-23. doi: 10.1136/thx.52.10.919.
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Bronchodilator responsiveness following a negative methacholine challenge test.乙酰甲胆碱激发试验阴性后的支气管扩张剂反应性
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Maximal degree of airway narrowing induced by methacholine and adenosine monophosphate: relationship with the decrease in forced vital capacity.乙酰甲胆碱和单磷酸腺苷引起的气道狭窄最大程度：与用力肺活量下降的关系。
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Evidence for an atypical receptor mediating the augmented bronchoconstrictor response to adenosine induced by allergen challenge in actively sensitized Brown Norway rats.在主动致敏的棕色挪威大鼠中，存在一种非典型受体介导变应原激发后对腺苷增强的支气管收缩反应的证据。
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本文引用的文献

1
Time course of changes in adenosine 5'-monophosphate airway responsiveness with inhaled heparin in allergic asthma.吸入肝素治疗过敏性哮喘时5'-单磷酸腺苷气道反应性的变化时间进程
J Allergy Clin Immunol. 1997 Mar;99(3):338-44. doi: 10.1016/s0091-6749(97)70051-4.
2
DNA antisense therapy for asthma in an animal model.动物模型中哮喘的DNA反义疗法。
Nature. 1997 Feb 20;385(6618):721-5. doi: 10.1038/385721a0.
3
In vivo role of the adenosine A3 receptor: N6-2-(4-aminophenyl)ethyladenosine induces bronchospasm in BDE rats by a neurally mediated mechanism involving cells resembling mast cells.腺苷 A3 受体的体内作用：N6-2-(4-氨基苯基)乙基腺苷通过一种涉及类似肥大细胞的神经介导机制在支气管扩张剂激发（BDE）大鼠中诱发支气管痉挛。
J Pharmacol Exp Ther. 1996 Dec;279(3):1148-56.
4
Effect of allergen avoidance at high altitude on direct and indirect bronchial hyperresponsiveness and markers of inflammation in children with allergic asthma.高海拔地区避免接触变应原对过敏性哮喘儿童直接和间接支气管高反应性及炎症标志物的影响
Thorax. 1996 Jun;51(6):582-4. doi: 10.1136/thx.51.6.582.
5
Activated memory T helper cells in bronchoalveolar lavage fluid from patients with atopic asthma: relation to asthma symptoms, lung function, and bronchial responsiveness.特应性哮喘患者支气管肺泡灌洗液中活化的记忆性辅助性T细胞：与哮喘症状、肺功能及支气管反应性的关系
Thorax. 1993 Jan;48(1):26-32. doi: 10.1136/thx.48.1.26.
6
Relative potencies and time course of changes in adenosine 5'-monophosphate airway responsiveness with inhaled furosemide and bumetanide in asthma.吸入速尿和布美他尼后哮喘患者气道对5'-单磷酸腺苷反应性变化的相对效能及时间过程
J Allergy Clin Immunol. 1993 Aug;92(2):288-97. doi: 10.1016/0091-6749(93)90172-c.
7
Nonbronchodilator effects of inhaled beta 2 agonists. Greater protection against adenosine monophosphate- than methacholine-induced bronchoconstriction in asthma.吸入性β2激动剂的非支气管扩张作用。在哮喘中，对单磷酸腺苷诱导的支气管收缩的保护作用大于对乙酰甲胆碱诱导的支气管收缩的保护作用。
Am J Respir Crit Care Med. 1994 Aug;150(2):381-7. doi: 10.1164/ajrccm.150.2.8049819.
8
Effect of inhaled frusemide on responses of airways to bradykinin and adenosine 5'-monophosphate in asthma.吸入速尿对哮喘患者气道对缓激肽和5'-单磷酸腺苷反应的影响。
Thorax. 1994 May;49(5):485-91. doi: 10.1136/thx.49.5.485.
9
Release of mast-cell-derived mediators after endobronchial adenosine challenge in asthma.
Am J Respir Crit Care Med. 1995 Mar;151(3 Pt 1):624-9. doi: 10.1164/ajrccm/151.3_Pt_1.624.
10
Renaissance of the effector role of the mast cell in bronchial asthma.肥大细胞在支气管哮喘中效应作用的复兴。
Ann Ital Med Int. 1995 Apr-Jun;10(2):126-33.

Adenosine bronchoprovocation: a promising marker of allergic inflammation in asthma?

作者信息

Polosa R, Holgate S T

机构信息

Istituto Malattie Apparato Respiratorio, University of Catania, Italy.

出版信息

Thorax. 1997 Oct;52(10):919-23. doi: 10.1136/thx.52.10.919.

DOI:10.1136/thx.52.10.919
PMID:9404382
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1758427/
Abstract
摘要