Raguin G, Leruez-Ville M, Gregoire V, Deplanche M, Leport C, Morinet F, Vilde J L
Service de Maladies Infectieuses et Tropicales, Hôpital Bichat-Claude Bernard, Paris, France.
Eur J Clin Microbiol Infect Dis. 1997 Oct;16(10):760-2. doi: 10.1007/BF01709261.
In a prospective study to determine the prevalence of parvovirus B19 in adult patients positive for the human immunodeficiency virus, a series of 55 consecutively presenting patients was tested for antibodies to parvovirus B19 and parvovirus B19 DNA. Specific IgG antibodies were detected in 96% of cases; specific IgM antibodies were present in 10%. Viral DNA was not detected in any of the sera analysed by polymerase chain reaction. Anemia could not be correlated with the presence of either IgG or IgM antibodies to parvovirus B19. Thus, no evidence of acute or chronic parvovirus B19 infection was found in the 55 patients. These findings suggest that active parvovirus B19 infection is uncommon in HIV-infected patients.
在一项旨在确定人类免疫缺陷病毒阳性成年患者中细小病毒B19感染率的前瞻性研究中，对连续就诊的55例患者进行了细小病毒B19抗体和细小病毒B19 DNA检测。96%的病例检测到特异性IgG抗体；10%的病例存在特异性IgM抗体。通过聚合酶链反应分析的任何血清中均未检测到病毒DNA。贫血与细小病毒B19的IgG或IgM抗体的存在无相关性。因此，在这55例患者中未发现急性或慢性细小病毒B19感染的证据。这些发现表明，在HIV感染患者中，活动性细小病毒B19感染并不常见。
