Vogt D, Curet M, Pitcher D, Josloff R, Milne R L, Zucker K
Department of Surgery, University of New Mexico, Presbyterian Medical Center, Albuquerque 87131-5341, USA.
Am J Surg. 1997 Dec;174(6):709-14. doi: 10.1016/s0002-9610(97)00197-9.
Recently, investigators have reported the use of endoscopic myotomy in the treatment of esophageal achalasia. As with the open operation, considerable disagreement exists regarding the appropriate length of the myotomy and the need for a concomitant antireflux procedure.
Patients presenting with symptomatic achalasia between 1993 and 1997 were included in this prospective study. Preoperative studies included barium upper gastrointestinal study, endoscopy, and esophageal manometry. Laparoscopic myotomy was completed in all 20 patients; 18 had concomitant Toupet fundoplication.
Operative times ranged from 95 to 345 minutes (mean 216). Blood loss ranged from 50 to 300 cc (mean 100 cc). There were 7 minor complications (5 mucosal injuries repaired laparoscopically, 1 bile leak and 1 splenic capsular tear). Nine patients began a liquid diet on the first day postoperatively; 19 were tolerating liquids by postoperative day 3. Hospital stay ranged from 2 to 20 days (mean 5). Eighteen patients had complete relief of dysphagia, with less than one reflux episode per month. One individual continues to have mild persistent solid food dysphagia. Another patient initially did well but subsequently developed mild recurrent dysphagia and reflux. One patient required laparoscopic take-down of the wrap because of recurrent dysphagia and now has no problems swallowing, but does complain of mild reflux. Two other patients also have mild reflux, 1 of whom did not undergo fundoplication.
Laparoscopic Heller myotomy can be performed safely with excellent results in patients with achalasia. Adding a partial fundoplication appears to help control postoperative symptoms of reflux. This procedure should be considered the procedure of choice in patients with symptomatic esophageal achalasia.
最近,研究人员报道了内镜下肌切开术治疗食管贲门失弛缓症。与开放手术一样,关于肌切开术的合适长度以及是否需要同时进行抗反流手术存在相当大的分歧。
1993年至1997年间出现症状性贲门失弛缓症的患者纳入本前瞻性研究。术前检查包括上消化道钡餐检查、内镜检查和食管测压。所有20例患者均完成了腹腔镜肌切开术;18例同时进行了Toupet胃底折叠术。
手术时间为95至345分钟(平均216分钟)。失血量为50至300毫升(平均100毫升)。有7例轻微并发症(5例腹腔镜下修复的黏膜损伤、1例胆漏和1例脾包膜撕裂)。9例患者术后第一天开始进流食;19例患者术后第3天能耐受流食。住院时间为2至20天(平均5天)。18例患者吞咽困难完全缓解,每月反流发作少于1次。1例患者仍有轻度持续性固体食物吞咽困难。另1例患者最初情况良好,但随后出现轻度复发性吞咽困难和反流。1例患者因复发性吞咽困难需要腹腔镜拆除胃底折叠术,现在吞咽没有问题,但确实抱怨有轻度反流。另外2例患者也有轻度反流,其中1例未进行胃底折叠术。
腹腔镜Heller肌切开术可安全地用于贲门失弛缓症患者,效果良好。加做部分胃底折叠术似乎有助于控制术后反流症状。对于有症状的食管贲门失弛缓症患者,应考虑将此手术作为首选手术。