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一项双盲随机研究中颈脊髓背根神经节射频损伤的疗效:40℃与67℃治疗之间无差异。

The efficacy of radiofrequency lesioning of the cervical spinal dorsal root ganglion in a double blinded randomized study: no difference between 40 degrees C and 67 degrees C treatments.

作者信息

Slappendel Robert, Crul Ben J P, Braak Gerard J J, Geurts Jos W M, Booij Leo H D J, Voerman Victor F, de Boo Theo

机构信息

Department of Anesthesiology, Sint Maartenskliniek, P.O. Box 9011, 6500 GM Nijmegen, The Netherlands Pain Center, Institute for Anesthesiology, University Hospital Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands Department of Anesthesiology, Sint Anna Hospital, P.O. Box 10, 5340 BE Oss, The Netherlands Department of Anesthesiology, Rijnstate Hospital, P.O. Box 9555, 6800 TA Arnhem, The Netherlands.

出版信息

Pain. 1997 Nov;73(2):159-163. doi: 10.1016/S0304-3959(97)00094-8.

Abstract

The efficacy of radiofrequency lesion treatment of the cervical dorsal root ganglion (RF-DRG) in cervicobrachialgia was investigated in 61 patients by a randomized prospective double blinded study. Before lesion treatment the putative pain provoking spinal root was identified by diagnostic blocks with a local anesthetic agent. One group of patients (n = 32, group I) was treated with a radiofrequency lesion of 67 degrees C and in a control group (n = 29, group II) a temperature of 40 degrees C was applied. Three months after treatment a significant reduction in VAS scores was demonstrated in both groups. The outcome of the treatments was identical (VAS reduction: group I, 1.7; group II, 1.9; P = 0.001). In group I a VAS reduction of 3 or more occurred in 11/31 (34%) and in group II in 11/29 (38%) of patients. A VAS reduction of 2 or more occurred in group I in 15/31 (47%) and in group II in 15/29 (51%) of patients. This study suggests that treatment with 40 degrees C radiofrequency application of the dorsal root ganglion is equally effective as treatment at 67 degrees C. Further appraisal of this treatment is required.

摘要

通过一项随机前瞻性双盲研究,对61例颈臂痛患者进行了颈背根神经节射频损伤治疗(RF-DRG)的疗效研究。在损伤治疗前,通过使用局部麻醉剂进行诊断性阻滞来确定可能引发疼痛的脊神经根。一组患者(n = 32,第一组)接受67摄氏度的射频损伤治疗,对照组(n = 29,第二组)施加40摄氏度的温度。治疗三个月后,两组的视觉模拟评分(VAS)均显著降低。治疗结果相同(VAS降低:第一组为1.7;第二组为1.9;P = 0.001)。在第一组中,11/31(34%)的患者VAS降低3或更多,在第二组中,11/29(38%)的患者VAS降低3或更多。在第一组中,15/31(47%)的患者VAS降低2或更多,在第二组中,15/29(51%)的患者VAS降低2或更多。这项研究表明,背根神经节40摄氏度射频治疗与67摄氏度治疗同样有效。需要对这种治疗进行进一步评估。

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