Farr M, Kendall M J, Young D W, Meynell M J, Hawkins C F
Ann Rheum Dis. 1976 Apr;35(2):163-7. doi: 10.1136/ard.35.2.163.
Joint inflammation in rheumatoid arthritis has been assessed, and the most useful guides to disease activity were determined by analysis of synovial fluid and blood together with the history of joint disability. The patient's own evaluation of the amount of pain suffered was the most useful clinical assessment. Differential cell count and glucose estimations were the most helpful guides in the synovial fluid, while C-reactive protein in the serum most accurately reflected disease activity. The effects of systemic steroids on these indices were studied, and the differences between seronegative and seropositive patients noted.
对类风湿性关节炎的关节炎症进行了评估,并通过对滑液和血液的分析以及关节残疾史来确定疾病活动的最有用指标。患者自身对所遭受疼痛程度的评估是最有用的临床评估。细胞分类计数和葡萄糖测定是滑液中最有帮助的指标,而血清中的C反应蛋白最准确地反映疾病活动。研究了全身性类固醇对这些指标的影响,并注意到血清阴性和血清阳性患者之间的差异。