• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

High interindividual variability of methadone enantiomer blood levels to dose ratios.

作者信息

Eap C B, Bertschy G, Baumann P, Finkbeiner T, Gastpar M, Scherbaum N

出版信息

Arch Gen Psychiatry. 1998 Jan;55(1):89-90. doi: 10.1001/archpsyc.55.1.89.

DOI:10.1001/archpsyc.55.1.89
PMID:9435768
Abstract
摘要

相似文献

1
High interindividual variability of methadone enantiomer blood levels to dose ratios.美沙酮对映体血药浓度与剂量比值存在高度个体间差异。
Arch Gen Psychiatry. 1998 Jan;55(1):89-90. doi: 10.1001/archpsyc.55.1.89.
2
Correlation between high methadone doses and methadone serum levels in methadone maintenance treatment (MMT) patients.美沙酮维持治疗(MMT)患者中高剂量美沙酮与美沙酮血清水平的相关性。
J Addict Dis. 2007;26(1):15-26. doi: 10.1300/J069v26n01_03.
3
Plasma methadone monitoring with methadone maintenance treatment.美沙酮维持治疗中的血浆美沙酮监测
Drug Alcohol Depend. 1994 Aug;36(1):69-71; author reply 73-5. doi: 10.1016/0376-8716(94)90012-4.
4
[Serum methadone monitoring in addicts on methadone maintenance treatment].
Ugeskr Laeger. 1988 May 30;150(22):1352-5.
5
Replacement of (R)-methadone by a double dose of (R,S)-methadone in addicts: interindividual variability of the (R)/(S) ratios and evidence of adaptive changes in methadone pharmacokinetics.在成瘾者中用双倍剂量的(R,S)-美沙酮替代(R)-美沙酮:(R)/(S)比值的个体间变异性和美沙酮药代动力学适应性变化的证据
Eur J Clin Pharmacol. 1996;50(5):385-9. doi: 10.1007/s002280050128.
6
Interindividual variability of the clinical pharmacokinetics of methadone: implications for the treatment of opioid dependence.美沙酮临床药代动力学的个体间变异性:对阿片类药物依赖治疗的影响。
Clin Pharmacokinet. 2002;41(14):1153-93. doi: 10.2165/00003088-200241140-00003.
7
The use of plasma levels to optimize methadone maintenance treatment.利用血浆水平优化美沙酮维持治疗。
Drug Alcohol Depend. 1992 Aug;30(3):241-6. doi: 10.1016/0376-8716(92)90058-k.
8
Dose, Plasma Level, and Treatment Outcome Among Methadone Patients in Shanghai, China.中国上海美沙酮治疗患者的剂量、血药浓度与治疗结果
Neurosci Bull. 2016 Dec;32(6):538-544. doi: 10.1007/s12264-016-0059-0. Epub 2016 Sep 10.
9
Utilization of plasma and urine methadone concentration measurements to limit narcotics use in methadone maintenance patients: II. Generation of plasma concentration response curves.利用血浆和尿液美沙酮浓度测量来限制美沙酮维持治疗患者的麻醉药品使用:II. 血浆浓度反应曲线的生成
J Addict Dis. 1995;14(1):85-108. doi: 10.1300/J069v14n01_09.
10
Contingent methadone dose increases as a method for reducing illicit opiate use in detoxification patients.应急美沙酮剂量增加作为减少戒毒患者非法阿片类药物使用的一种方法。
NIDA Res Monogr. 1984;55:178-84.

引用本文的文献

1
The effect of a methadone reformulation on opioid agonist treatment outcomes: A population-based study in British Columbia, Canada, 2013-14.美沙酮配方改革对阿片类激动剂治疗结果的影响:加拿大不列颠哥伦比亚省 2013-2014 年的一项基于人群的研究。
J Subst Abuse Treat. 2022 Jul;138:108714. doi: 10.1016/j.jsat.2021.108714. Epub 2021 Dec 28.
2
The Impact of Opioids on Cardiac Electrophysiology.阿片类药物对心脏电生理学的影响。
Curr Cardiol Rev. 2016;12(1):27-36. doi: 10.2174/1573403x1201160126122405.
3
The effectiveness of opioid substitution treatments for patients with opioid dependence: a systematic review and multiple treatment comparison protocol.
阿片类药物替代疗法对阿片类药物依赖患者的有效性:一项系统评价和多种治疗比较方案
Syst Rev. 2014 Sep 19;3:105. doi: 10.1186/2046-4053-3-105.
4
Genetic influence on methadone treatment outcomes in patients undergoing methadone maintenance treatment for opioid addiction: a pilot study.遗传因素对接受美沙酮维持治疗的阿片类药物成瘾患者美沙酮治疗结局的影响:一项初步研究。
Neuropsychiatr Dis Treat. 2014 Aug 19;10:1503-8. doi: 10.2147/NDT.S66234. eCollection 2014.
5
Pharmacologic evidence to support clinical decision making for peripartum methadone treatment.支持围产期美沙酮治疗的临床决策的药理学证据。
Psychopharmacology (Berl). 2013 Jan;225(2):441-51. doi: 10.1007/s00213-012-2833-7. Epub 2012 Aug 25.
6
Serum concentrations of opioids when comparing two switching strategies to methadone for cancer pain.比较两种用于癌症疼痛的美沙酮转换策略时的阿片类药物血清浓度。
Eur J Clin Pharmacol. 2012 Aug;68(8):1147-56. doi: 10.1007/s00228-012-1228-3. Epub 2012 Feb 29.
7
Estimated infant exposure to enantiomer-specific methadone levels in breastmilk.估算婴儿通过母乳摄入的对映体特异性美沙酮水平。
Breastfeed Med. 2011 Dec;6(6):377-84. doi: 10.1089/bfm.2010.0060. Epub 2011 Feb 24.
8
Contribution of the activities of CYP3A, CYP2D6, CYP1A2 and other potential covariates to the disposition of methadone in patients undergoing methadone maintenance treatment.CYP3A、CYP2D6、CYP1A2及其他潜在协变量的活性对接受美沙酮维持治疗患者中美沙酮处置的贡献。
Br J Clin Pharmacol. 2009 Jan;67(1):29-37. doi: 10.1111/j.1365-2125.2008.03312.x.
9
Sublingual buprenorphine/naloxone precipitated withdrawal in subjects maintained on 100mg of daily methadone.在每日服用100毫克美沙酮维持治疗的受试者中,舌下含服丁丙诺啡/纳洛酮引发了戒断反应。
Drug Alcohol Depend. 2007 Oct 8;90(2-3):261-9. doi: 10.1016/j.drugalcdep.2007.04.006. Epub 2007 May 22.
10
Within- and between- subject variability in methadone pharmacokinetics and pharmacodynamics in methadone maintenance subjects.美沙酮维持治疗患者体内美沙酮药代动力学和药效学的个体内及个体间变异性。
Br J Clin Pharmacol. 2005 Oct;60(4):404-13. doi: 10.1111/j.1365-2125.2005.02464.x.