Margo C E, Mulla Z D
Department of Ophthalmology, College of Medicine, University of South Florida, Tampa 33612, USA.
Arch Ophthalmol. 1998 Feb;116(2):195-8. doi: 10.1001/archopht.116.2.195.
To determine the relative frequencies, average annual incidences, and patient characteristics of non-basal cell and non-squamous cell malignant neoplasms of the eyelid in a defined geographic population.
A retrospective study using the Florida Cancer Data System to identify malignant tumors of the eyelid, except for basal cell and squamous cell carcinomas, from 1981 through 1994. Cases were limited to persons who resided within Florida.
Incidence of histologically confirmed malignant eyelid tumors.
Two hundred six primary malignant eyelid tumors were identified. The 3 most common, in order of frequency, were melanoma, sebaceous carcinoma, and lymphoma. The median age at diagnosis for all patients was 73 years. Only 3 of the 206 malignant neoplasms occurred in blacks. The annual incidence of eyelid melanoma and sebaceous carcinoma in whites older than 20 years was 0.6 and 0.5 per million, respectively. Kaposi sarcoma was the most common type of mesenchymal tumor. Eleven different histologic types of lymphoma were found in the eyelid. Only 2 of 27 lymphomas had T-cell lineage.
Malignant tumors of the eyelid other than basal cell and squamous cell carcinoma are uncommon and usually occur in elderly white persons. Primary eyelid tumors of any type are rare in blacks. The risk of a non-basal cell and non-squamous cell malignant neoplasm of the eyelid in Florida is 6.4 times greater for whites than for blacks (95% confidence interval [CI], 2.1-20.2). A variety of B-cell lymphomas can be manifested as primary eyelid tumors.
确定特定地理区域人群中眼睑非基底细胞和非鳞状细胞恶性肿瘤的相对频率、年均发病率及患者特征。
一项回顾性研究，利用佛罗里达癌症数据系统识别1981年至1994年间除基底细胞癌和鳞状细胞癌外的眼睑恶性肿瘤。病例仅限于居住在佛罗里达州的人。
组织学确诊的眼睑恶性肿瘤发病率。
共识别出206例原发性眼睑恶性肿瘤。按频率排序，最常见的3种肿瘤依次为黑色素瘤、皮脂腺癌和淋巴瘤。所有患者的诊断中位年龄为73岁。206例恶性肿瘤中仅有3例发生在黑人患者。20岁以上白人中眼睑黑色素瘤和皮脂腺癌的年发病率分别为百万分之0.6和0.5。卡波西肉瘤是最常见的间叶组织肿瘤类型。在眼睑中发现了11种不同组织学类型的淋巴瘤。27例淋巴瘤中仅有2例为T细胞谱系。
除基底细胞癌和鳞状细胞癌外，眼睑恶性肿瘤并不常见，通常发生在老年白人中。黑人中任何类型的原发性眼睑肿瘤都很罕见。佛罗里达州白人发生眼睑非基底细胞和非鳞状细胞恶性肿瘤的风险是黑人的6.4倍（95%置信区间[CI]，2.1 - 20.2）。多种B细胞淋巴瘤可表现为原发性眼睑肿瘤。
