Graeff F G
Laboratório de Psicofarmacologia, Universidade de São Paulo, Brazil.
Psychiatr Clin North Am. 1997 Dec;20(4):723-39. doi: 10.1016/s0193-953x(05)70342-7.
Since its identification in neurons of the central nervous systems (CNS), serotonin (5-HT) has been implicated in the pathophysiology of psychiatric disorders, such as schizophrenia, depression, generalized anxiety disorder (GAD), panic disorder (PD), and obsessive-compulsive disorder (OCD). These findings have stimulated research on brain 5-HT pathways, especially during the last two decades as more selective drugs have been introduced into medical practice. This article reviews selected topics relevant for psychiatry.
