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氟哌啶醇、氟西汀及安慰剂治疗阿尔茨海默病激越症状的初步研究

Pilot study of haloperidol, fluoxetine, and placebo for agitation in Alzheimer's disease.

作者信息

Auchus A P, Bissey-Black C

机构信息

Department of Neurology and Center for Geriatrics, Emory University School of Medicine, Atlanta, Georgia, USA.

出版信息

J Neuropsychiatry Clin Neurosci. 1997 Fall;9(4):591-3. doi: 10.1176/jnp.9.4.591.

DOI:10.1176/jnp.9.4.591
PMID:9447502
Abstract

This pilot study compared haloperidol, fluoxetine, and placebo for reduction of agitation in 15 outpatients with AD. The two drugs were no more effective than placebo at reducing agitation in these subjects; however, both drugs produced more toxicity than did placebo.

摘要

这项初步研究比较了氟哌啶醇、氟西汀和安慰剂对15名门诊阿尔茨海默病患者激越症状的缓解作用。在减轻这些患者的激越症状方面,这两种药物并不比安慰剂更有效;然而,这两种药物产生的毒性都比安慰剂更大。

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