Kramer M H, Sorhage F E, Goldstein S T, Dalley E, Wahlquist S P, Herwaldt B L
Epidemic Intelligence Service (Epidemiology Program Office), Centers for Disease Control and Prevention, Atlanta, Georgia 30341-3724, USA.
Clin Infect Dis. 1998 Jan;26(1):27-33. doi: 10.1086/516271.
In the summer of 1994, an outbreak of cryptosporidiosis occurred among visitors to a state park in New Jersey. We enrolled 185 persons in a cohort study, 38 (20.5%) of whom had laboratory-confirmed cryptosporidiosis or gastrointestinal illness that met our clinical case definition. Having any exposure to lake water (e.g., swimming) was strongly associated with illness (P < .001). The outbreak lasted 4 weeks and affected an estimated 2,070 persons. The most likely sources of the outbreak were contaminated runoff of rainwater and infected bathers. This outbreak of cryptosporidiosis is the first reported to be associated with recreational exposure to lake water. Our investigation shows that even a large and ongoing outbreak may not be detected for several weeks. Health professionals and persons at high risk for severe cryptosporidiosis should be aware that recreational water can be a source of cryptosporidium infection.
1994年夏天,新泽西州一个州立公园的游客中爆发了隐孢子虫病。我们对185人进行了队列研究,其中38人(20.5%)经实验室确诊患有隐孢子虫病或符合我们临床病例定义的胃肠道疾病。接触湖水(如游泳)与患病密切相关(P < .001)。疫情持续了4周,估计有2070人受到影响。疫情最可能的源头是被污染的雨水径流和受感染的游泳者。此次隐孢子虫病疫情是首次报告与娱乐性接触湖水有关。我们的调查表明,即使是大规模且持续的疫情,也可能在数周内未被发现。卫生专业人员和严重隐孢子虫病高危人群应意识到,娱乐用水可能是隐孢子虫感染的一个来源。