Siegel S R, Oh W
Acta Paediatr Scand. 1976 Jul;65(4):481-5. doi: 10.1111/j.1651-2227.1976.tb04917.x.
Sixty clinically well infants of various gestational ages (27 to 40 weeks) were studied from 24-40 hours after birth to evaluate glomerular filtration rate and renal excretion rate of sodium at various stages of fetal maturation. Creatinine clearance was directly related to gestational as (r = 0.643). Fractional sodium excretion was inversely related to gestational age (r = -0.755). The renal functions of small for gestational age infants were similar to those of full-term infants whose birth weights were appropriate for gestational age. The data showed that the glomerular functions of an infant below 32 weeks of gestation were more predominant than the tubular function resulting in a greater fractional sodium excretion rate and higher urinary Na loss in infants of this gestational age, when compared with the more mature infants.
对60名不同胎龄（27至40周）的临床健康婴儿进行了研究，从出生后24至40小时开始，以评估胎儿成熟各阶段的肾小球滤过率和钠的肾排泄率。肌酐清除率与胎龄直接相关（r = 0.643）。钠排泄分数与胎龄呈负相关（r = -0.755）。小于胎龄儿的肾功能与出生体重符合胎龄的足月儿相似。数据表明，与更成熟的婴儿相比，胎龄低于32周的婴儿肾小球功能比肾小管功能更占优势，导致该胎龄婴儿的钠排泄分数率更高，尿钠丢失更多。
