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Radioimmunoassay for 3,3',5'-triiodothyronine (reverse T3, R-T3) in unextracted human serum.

作者信息

Hüfner M, Grussendorf M

出版信息

Clin Chim Acta. 1976 Jun 15;69(3):497-504. doi: 10.1016/0009-8981(76)90124-8.

DOI:10.1016/0009-8981(76)90124-8
PMID:947601
Abstract

Highly specific antibodies against 3,3',5'-triiodothyronine (reverse T3, R-T3) have been produced in rabbits. The crossreaction with T4 is about 0.05%. A radioimmunoassay for R-T3 in unextracted serum was developed. ANS is used for blocking the binding of tracer and endogenous R-T3 to TBG. The sensitivity to the assay is 0.06 ng/ml plasma. The mean normal R-T3 concentration is 0.20 ng/ml. Thyrotoxic patients show elevated levels; in most hypothyroid patients R-T3 concentrations are below the detection limit.

摘要

相似文献

1
Radioimmunoassay for 3,3',5'-triiodothyronine (reverse T3, R-T3) in unextracted human serum.
Clin Chim Acta. 1976 Jun 15;69(3):497-504. doi: 10.1016/0009-8981(76)90124-8.
2
The influence of thyroxine on the serum free triiodothyronine concentration.甲状腺素对血清游离三碘甲状腺原氨酸浓度的影响。
Clin Chim Acta. 1976 Mar 15;67(3):223-30. doi: 10.1016/0009-8981(76)90330-2.
3
Radioimmunoassays of T3, r-T3 and r-T'2 in human serum.人血清中T3、反T3和反T2的放射免疫测定
Acta Med Scand Suppl. 1979;624:19-24. doi: 10.1111/j.0954-6820.1979.tb00713.x.
4
Determination of triiodothyronine in red blood cells by radioimmunoassay.用放射免疫分析法测定红细胞中的三碘甲状腺原氨酸。
Endocrinol Jpn. 1976 Jun;23(3):207-13. doi: 10.1507/endocrj1954.23.207.
5
A radioimmunoassay for 3,3',5'-L-triiodothyronine (reverse T3): assessment of thyroid gland content and serum measurements in conditions of normal and altered thyroidal economy and following administration of thyrotropin releasing hormone (TRH) and thyrotropin (TSH).3,3',5'-L-三碘甲腺原氨酸（反式T3）的放射免疫分析：在甲状腺功能正常和改变的情况下以及给予促甲状腺激素释放激素（TRH）和促甲状腺激素（TSH）后对甲状腺含量和血清测量值的评估
J Clin Endocrinol Metab. 1977 Apr;44(4):660-72. doi: 10.1210/jcem-44-4-660.
6
Simultaneous measurement of free thyroxine and free 3,5,3'-triiodothyronine in undiluted serum by direct equilibrium dialysis/radioimmunoassay: evidence that free triiodothyronine and free thyroxine are normal in many patients with the low triiodothyronine syndrome.通过直接平衡透析/放射免疫分析法同时测定未稀释血清中的游离甲状腺素和游离三碘甲状腺原氨酸：许多低三碘甲状腺原氨酸综合征患者游离三碘甲状腺原氨酸和游离甲状腺素正常的证据。
Thyroid. 1998 Mar;8(3):249-57. doi: 10.1089/thy.1998.8.249.
7
A radioimmunoassay for measurement of 3,3',5'-triiodothyronine (reverse T3).一种用于测量3,3',5'-三碘甲状腺原氨酸（反式T3）的放射免疫测定法。
J Clin Invest. 1974 Sep;54(3):583-92. doi: 10.1172/JCI107795.
8
A simple and rapid radioimmunoassay of triiodothyronine in unextracted serum.未提取血清中三碘甲状腺原氨酸的简单快速放射免疫分析法。
J Nucl Med. 1976 May;17(5):411-6.
9
The radioimmunoassay of 3,3',5' - triiodothyronine (reverse T3) in unextracted human serum.未提取人血清中3,3',5'-三碘甲状腺原氨酸（反式T3）的放射免疫测定
Clin Endocrinol (Oxf). 1976 Nov;5(6):631-41. doi: 10.1111/j.1365-2265.1976.tb03866.x.
10
Simultaneous measurement of triiodothyronine and thyroxine in unextracted serum samples using a double-tracer radioimmunoassay method.使用双示踪放射免疫分析法同时测定未提取血清样本中的三碘甲状腺原氨酸和甲状腺素。
J Nucl Med. 1977 Mar;18(3):300-4.

引用本文的文献

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Br J Clin Pharmacol. 1981 Dec;12(6):825-8. doi: 10.1111/j.1365-2125.1981.tb01314.x.
2
Effect of timolol on clinical features and echocardiographic assessment of left ventricular function in hyperthyroidism.噻吗洛尔对甲状腺功能亢进症临床特征及左心室功能超声心动图评估的影响。
Br J Clin Pharmacol. 1983 Dec;16(6):609-14. doi: 10.1111/j.1365-2125.1983.tb02229.x.
3
3,3',5'-Triiodothyronine (Reverse T3) in amniotic fluid and cord serum.
羊水和脐血血清中的3,3',5'-三碘甲状腺原氨酸（反式T3）
Eur J Pediatr. 1977 Jul 1;125(3):213-7. doi: 10.1007/BF00480599.