向下注视时原发性位置性向上眼球震颤增强：一名多发性硬化症患者的临床病理研究
Primary position upbeat nystagmus increased on downward gaze: clinicopathologic study of a patient with multiple sclerosis.
作者信息
Ohkoshi N, Komatsu Y, Mizusawa H, Kanazawa I
机构信息
Department of Neurology, University of Tsukuba, Ibaraki, Japan.
出版信息
Neurology. 1998 Feb;50(2):551-3. doi: 10.1212/wnl.50.2.551.
PMID:9484398
Abstract
We describe a patient with multiple sclerosis who had primary position upbeat nystagmus that increased in amplitude on downward gaze. Pathologic examination revealed demyelinating foci with macrophage infiltration in the lower medulla, involving the perihypoglossal nuclei (the intercalatus nuclei). A lesion of this region may be responsible for upbeat nystagmus.
摘要
我们描述了一名患有多发性硬化症的患者，其存在原发性位置性上跳性眼球震颤，向下注视时振幅增加。病理检查显示延髓下部有脱髓鞘病灶，并伴有巨噬细胞浸润，累及舌下神经周核（中间核）。该区域的病变可能是上跳性眼球震颤的病因。
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