Berutti E, Marini R, Angeretti A
Department of Endodontics, School of Dentistry, Turin University, Italy.
J Endod. 1997 Dec;23(12):725-7. doi: 10.1016/S0099-2399(97)80342-1.
Dentinal tubules of human root canal walls were infected with a known bacterial isolate. The teeth were divided into two groups and the root canals instrumentated. Different types of canal irrigant were used for each group. In group A, 5% NaOCl was followed by a 10% EDTA rinse and neutralized with a final physiological solution rinse. In Group B, 10% EDTA, a tensioactive agent (TRITON), and 5% NaOCl were used in sequence, with a final physiological solution rinse to neutralize the action of the agents used. Histological examination of group A specimens showed a residual area of infection extending from the canal lumen to a mean depth of 300 microns. Histological examination of group B specimens showed an infection-free area of tubules to a mean depth of 130 microns. Below this was an infected area of variable extent. In some group B sections, no infection was found.
将人类根管壁的牙本质小管接种已知的细菌分离株。将牙齿分为两组并对根管进行预备。每组使用不同类型的根管冲洗剂。A组先用5%次氯酸钠，接着用10%乙二胺四乙酸（EDTA）冲洗，最后用生理溶液冲洗以中和残留作用。B组依次使用10%乙二胺四乙酸（EDTA）、一种表面活性剂（吐温）和5%次氯酸钠，最后用生理溶液冲洗以中和所用试剂的作用。A组标本的组织学检查显示，感染残留区域从根管腔延伸至平均深度300微米处。B组标本的组织学检查显示，牙本质小管平均深度130微米处为无感染区域。在此之下是不同范围的感染区域。在一些B组切片中未发现感染。
