BCL1，一种慢性淋巴细胞白血病的小鼠模型：利用表面免疫球蛋白独特型检测和治疗肿瘤。 - Suppr

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超能文献

BCL1, a murine model for chronic lymphocytic leukemia: use of the surface immunoglobulin idiotype for the detection and treatment of tumor.

作者信息

Krolick K A, Isakson P C, Uhr J W, Vitetta E S

出版信息

Immunol Rev. 1979;48:81-106. doi: 10.1111/j.1600-065x.1979.tb00299.x.

DOI:10.1111/j.1600-065x.1979.tb00299.x

PMID:94899

Abstract

摘要

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BCL1, a murine model for chronic lymphocytic leukemia: use of the surface immunoglobulin idiotype for the detection and treatment of tumor.BCL1，一种慢性淋巴细胞白血病的小鼠模型：利用表面免疫球蛋白独特型检测和治疗肿瘤。

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Growth inhibition of a B cell leukemia: evidence implicating an anti-idiotype immune response for protective tumor immunity.一种B细胞白血病的生长抑制：提示抗独特型免疫反应参与保护性肿瘤免疫的证据。

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Immunologic regulation of lymphoid tumor cells: model systems for lymphocyte function.

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Immunization with idiotypic immunoglobulin protects against development of B lymphocytic leukemia, but emerging tumor cells can evade antibody attack by modulation.用独特型免疫球蛋白进行免疫可预防B淋巴细胞白血病的发生，但新出现的肿瘤细胞可通过调节作用逃避抗体攻击。

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Anti-idiotype sera raised against surface immunoglobulin of human neoplastic lymphocytes.针对人类肿瘤淋巴细胞表面免疫球蛋白产生的抗独特型血清。

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Molecules recognized by anti-idiotypic monoclonal antibodies to the B cell lymphoma, BCL1.被针对B细胞淋巴瘤BCL1的抗独特型单克隆抗体识别的分子。

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The nature of the immunoglobulin G on the surface of B lymphocytes in chronic lymphocytic leukemia.慢性淋巴细胞白血病中B淋巴细胞表面免疫球蛋白G的性质。

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Characterization of the spontaneous murine B cell leukemia (BCL1). III. Evidence for monoclonality by using an anti-idiotype antibody.自发性小鼠B细胞白血病（BCL1）的特征。III. 使用抗独特型抗体证明单克隆性。

J Immunol. 1979 May;122(5):1649-54.

Differentiation capacity and other properties of the leukemic cells of chronic lymphocytic leukemia.慢性淋巴细胞白血病白血病细胞的分化能力及其他特性。

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Idiotypic determinants on the surface immunoglobulin of neoplastic lymphocytes: a therapeutic target.肿瘤淋巴细胞表面免疫球蛋白的独特型决定簇：一个治疗靶点。

Fed Proc. 1977 Aug;36(9):2268-71.

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Induction of tumor immunity by intact irradiated leukemic B cells (BCL1) bearing a tumor-associated cell-surface idiotype and the costimulatory B7 molecule.携带肿瘤相关细胞表面独特型和共刺激分子B7的完整照射白血病B细胞（BCL1）诱导肿瘤免疫。

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BCL1, a murine model of prolymphocytic leukemia. I. Effect of splenectomy on growth kinetics and organ distribution.BCL1，一种幼淋巴细胞白血病的小鼠模型。I. 脾切除对生长动力学和器官分布的影响。

Am J Pathol. 1981 Dec;105(3):295-305.

Acquisition of cell surface IgD after in vitro culture of neoplastic B cells from the murine tumor BCL1.对来自小鼠肿瘤BCL1的肿瘤性B细胞进行体外培养后获得细胞表面IgD。

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BCL1, a murine model of prolymphocytic leukemia. II. Morphology and ultrastructure.BCL1，一种幼淋巴细胞白血病的小鼠模型。II. 形态学与超微结构

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In vivo therapy of a murine B cell tumor (BCL1) using antibody-ricin A chain immunotoxins.使用抗体-蓖麻毒素A链免疫毒素对小鼠B细胞肿瘤（BCL1）进行体内治疗。

J Exp Med. 1982 Jun 1;155(6):1797-809. doi: 10.1084/jem.155.6.1797.

Induction of proliferation and differentiation of neoplastic B cells by anti-immunoglobulin and T-cell factors.抗免疫球蛋白和T细胞因子诱导肿瘤性B细胞的增殖与分化

Proc Natl Acad Sci U S A. 1981 Apr;78(4):2507-11. doi: 10.1073/pnas.78.4.2507.

Mechanisms of tumour cell escape encountered in treating lymphocytic leukaemia with anti-idiotypic antibody.用抗独特型抗体治疗淋巴细胞白血病时遇到的肿瘤细胞逃逸机制。

Br J Cancer. 1984 May;49(5):547-57. doi: 10.1038/bjc.1984.88.

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