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豚鼠的皮肤表面脂质

Skin surface lipids of the guinea pig.

作者信息

Downing D T, Sharaf D M

出版信息

Biochim Biophys Acta. 1976 Jun 22;431(3):378-89. doi: 10.1016/0005-2760(76)90204-6.

DOI:10.1016/0005-2760(76)90204-6
PMID:949482
Abstract

Skin surface lipids of the guinea pig were found to contain sterol esters (33%), wax diesters (diacyl alkanediols) (24%), glycerol ether diesters (28%), free fatty alcohols (6%) and free sterols (9%). The sterol esters and diacyl alkanediols contained saturated fatty acids (40 and 67%, respectively) having straight and singly-branched chains and mono-unsaturated acids (60 and 33%,respectively) derived predominantly by delta 9-desaturation of C15 and C16 straight-chain saturated fatty-acid precursors. The 1-O-alkylglycerols and fatty acids from the glycerol ether diesters were both entirely saturated series containing straight, branched and multi-branched chains. Both the free and the esterified sterols consisted principally of cholesterol with a small proportion of lathosterol.

摘要

豚鼠皮肤表面脂质被发现含有甾醇酯(33%)、蜡二酯(二酰基链烷二醇)(24%)、甘油醚二酯(28%)、游离脂肪醇(6%)和游离甾醇(9%)。甾醇酯和二酰基链烷二醇含有饱和脂肪酸(分别为40%和67%),其具有直链和单分支链,以及单不饱和酸(分别为60%和33%),这些单不饱和酸主要由C15和C16直链饱和脂肪酸前体的δ9-去饱和作用产生。甘油醚二酯中的1-O-烷基甘油和脂肪酸均为完全饱和系列,包含直链、分支链和多分支链。游离甾醇和酯化甾醇主要都由胆固醇组成,还有一小部分羊毛甾醇。

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