Omar O, Pirayesh A, Mamalis N, Olson R J
John Moran Eye Center, Department of Ophthalmology, University of Utah School of Medicine, Salt Lake City 84132, USA.
J Cataract Refract Surg. 1998 Jan;24(1):107-13. doi: 10.1016/s0886-3350(98)80082-5.
To compare the formation of "glistenings" in acrylic intraocular lenses (IOLs) packaged in Wagon Wheel and AcryPak packaging systems.
John Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.
Acrylic IOLs in Wagon Wheel (WW) and AcryPak (AP) packaging were analyzed in vitro. The lenses were placed in a test chamber with a controlled temperature and evaluated every 48 hours for 336 hours. The presence of glistenings within the lens optic was assessed using slitlamp evaluation and a quantitative microscopic evaluation with an image analysis system.
When maintained at a constant temperature, the WW-packaged IOLs showed no glistening formation and the AP-packaged IOLs, significant glistening formation. Glistenings were noted in the WW-packaged IOLs only under fluctuating temperature conditions. Quantitative image analysis confirmed the presence of glistenings only in AP-packaged IOLs maintained at a constant temperature.
The glistenings in AcrySof IOLs were temperature dependent and confined to IOLs packaged in AcryPak folders and maintained at constant (body) temperatures. These findings are believed to be consistent with fluid formation within the acrylic optic, somehow related to the AcryPak packaging system.
比较采用“车轮式”（Wagon Wheel）和“丙烯酸包装”（AcryPak）包装系统包装的丙烯酸人工晶状体（IOL）中“闪光现象”的形成情况。
美国犹他州盐湖城犹他大学约翰·莫兰眼科中心。
对采用“车轮式”（WW）和“丙烯酸包装”（AP）包装的丙烯酸IOL进行体外分析。将晶状体置于温度可控的测试室中，每48小时评估一次，共评估336小时。使用裂隙灯评估和图像分析系统进行定量显微镜评估来评估晶状体光学部内闪光现象的存在情况。
在恒温条件下，采用“车轮式”包装的IOL未出现闪光现象，而采用“丙烯酸包装”的IOL出现了明显的闪光现象。仅在温度波动条件下，采用“车轮式”包装的IOL中才出现闪光现象。定量图像分析证实，仅在恒温条件下保存的采用“丙烯酸包装”的IOL中存在闪光现象。
AcrySof IOL中的闪光现象与温度有关，且仅限于采用“丙烯酸包装”文件夹包装并保持在恒定（体温）温度下的IOL。这些发现被认为与丙烯酸光学部内的液体形成一致，在某种程度上与“丙烯酸包装”系统有关。
