Schuur P M, Kasteren M E, Sabbe L, Vos M C, Janssens M M, Buiting A G
Department of Medical Microbiology, St. Elisabeth Hospital, Tilburg, The Netherlands.
Eur J Clin Microbiol Infect Dis. 1997 Dec;16(12):871-5. doi: 10.1007/BF01700552.
Aerococcus urinae is an uncommon urinary tract pathogen that causes infections predominantly in elderly persons with local or general predisposing conditions. During a one-year study, the clinical features of Aerococcus urinae urinary tract infections (> or = 10(5) cfu/ml) were investigated in two large medical microbiology laboratories in the Netherlands. The incidence of Aerococcus urinae urinary tract infections ranged between 0.31 and 0.44% for the two laboratories. The median age (range 35-95 years) of patients with this infection was 82.5 years for women and 77.5 for men. Men had significantly (p < 0.01) more local predisposing conditions than did women. Underlying systemic diseases such as diabetes mellitus, malignancy, and dementia were found in 67.5% of patients. Most patients (97.5%) had the classic signs of a urinary tract infection, but none of them developed serious symptoms. All isolates tested were susceptible to penicillin, amoxicillin, and nitrofurantoin, 78.3% were susceptible to norfloxacin, and all were resistant to sulfonamides. The majority of patients were treated with amoxicillin, amoxicillin with clavulanic acid, or norfloxacin.
尿液气球菌是一种不常见的泌尿道病原体，主要在有局部或全身易感因素的老年人中引起感染。在一项为期一年的研究中，荷兰两家大型医学微生物实验室对尿液气球菌引起的泌尿道感染（≥10⁵cfu/ml）的临床特征进行了调查。两家实验室尿液气球菌引起的泌尿道感染发病率在0.31%至0.44%之间。感染该菌的患者中位年龄（范围35 - 95岁）女性为82.5岁，男性为77.5岁。男性的局部易感因素显著多于女性（p < 0.01）。67.5%的患者存在如糖尿病、恶性肿瘤和痴呆等潜在全身性疾病。大多数患者（97.5%）有典型的泌尿道感染症状，但均未出现严重症状。所有检测的分离株对青霉素、阿莫西林和呋喃妥因敏感，78.3%对诺氟沙星敏感，对磺胺类药物均耐药。大多数患者接受阿莫西林、阿莫西林克拉维酸或诺氟沙星治疗。
