Wells A S, Read N W, Laugharne J D, Ahluwalia N S
Centre for Human Nutrition, University of Sheffield, Northern General Hospital, UK.
Br J Nutr. 1998 Jan;79(1):23-30. doi: 10.1079/bjn19980005.
The effects on mood of reducing dietary fat while keeping the energy constant were examined in ten male and ten female healthy volunteers aged between 20 and 37 years. Each volunteer consumed a diet containing 41% energy as fat for 1 month. For the second month half of the subjects changed to a low-fat diet (25% energy from fat) and the remainder continued to eat the diet containing 41% energy from fat. Changes in mood and blood lipid concentrations were assessed before, during and at the end of the study. Profile of mood states (POMS) ratings of anger-hostility significantly increased in the intervention group after 1 month on the low-fat diet, while during the same period there was a slight decline in anger-hostility in the control subjects (group F 6.72; df 1.14; P = 0.021). Tension-anxiety ratings declined in the control group consuming the higher fat diet but did not change in the group consuming the low-fat diet (group F 6.34; df 1.14; P = 0.025). There was a decline in fasting concentrations of HDL-cholesterol after the low-fat diet and a small increase in subjects consuming the medium-fat diet (group F 4.96; df 1.12; P = 0.046), but no significant changes in concentrations of total serum cholesterol, LDL-cholesterol or triacylglycerol were observed. The results suggest that a change in dietary fat content from 41 to 25% energy may have adverse effects on mood. The alterations in mood appear to be unrelated to changes in fasting plasma cholesterol concentrations.
在10名年龄在20至37岁之间的健康男性志愿者和10名健康女性志愿者中，研究了在保持能量恒定的情况下减少膳食脂肪对情绪的影响。每位志愿者食用了1个月含41%能量来自脂肪的饮食。在第二个月，一半受试者改为低脂饮食（25%能量来自脂肪），其余受试者继续食用含41%能量来自脂肪的饮食。在研究开始前、期间和结束时评估情绪和血脂浓度的变化。在低脂饮食1个月后，干预组的情绪状态量表（POMS）愤怒-敌意评分显著增加，而在同一时期，对照组的愤怒-敌意评分略有下降（F组6.72；自由度1.14；P = 0.021）。食用高脂肪饮食的对照组紧张-焦虑评分下降，但食用低脂饮食的组没有变化（F组6.34；自由度1.14；P = 0.025）。低脂饮食后高密度脂蛋白胆固醇的空腹浓度下降，食用中等脂肪饮食的受试者略有增加（F组4.96；自由度1.12；P = 0.046），但总血清胆固醇、低密度脂蛋白胆固醇或三酰甘油的浓度没有显著变化。结果表明，膳食脂肪含量从能量的41%降至25%可能对情绪产生不利影响。情绪变化似乎与空腹血浆胆固醇浓度的变化无关。
