Ferrara P, Zakin M M, Peña C, Paladini A C
Eur J Immunol. 1979 Dec;9(12):1020-3. doi: 10.1002/eji.1830091219.
Antigenic determinant areas were detected in bovine growth hormone fragments 6--124 and 125--149, the former being predominant. Reduction and carboxymethylation of disulfide bridge 53--164 destroys the immunological reactivity of the area which is little affected by reduction and carbamoylmethylation. All the activity found in fragment 6--124 seems to be concentrated in the sequence 87--124.
在牛生长激素片段6 - 124和125 - 149中检测到抗原决定簇区域，前者占主导。二硫键53 - 164的还原和羧甲基化破坏了该区域的免疫反应性，而该区域受还原和氨甲酰甲基化的影响较小。在片段6 - 124中发现的所有活性似乎都集中在87 - 124序列中。
