Sweeney C T, Kozlowski L T
Department of Biobehavioral Health, The Pennsylvania State University, University Park 16802, USA.
Pharmacol Biochem Behav. 1998 Mar;59(3):767-73. doi: 10.1016/s0091-3057(97)00567-4.
Effect of vent blocking on carbon monoxide (CO) exposure from a best-selling light cigarette was examined in 12 daily cigarette smokers. Mean CO boosts were not different from each other with (a) 0% filter vents blocked (5.0 ppm), (b) vents covered with lips (4.9 ppm), (c) 50% of vents covered with tape (4.8 ppm), and (d) vents covered with a pinch of the fingertips (4.9 ppm). A second study in another 12 smokers was conducted to replicate these findings as well as earlier findings that blocking vents doubles CO intake from 1-mg tar cigarettes. While blocking half the vents with fingers significantly increased CO boost from ultralight cigarettes (2.8 vs. 5.4 ppm, p < 0.001), it did not influence boosts from light cigarettes (6.3 vs. 6.5 ppm, p = 0.8). The lowest yield cigarettes (1 mg tar) may be special. Smoking machine simulations provide poor models of human smoke intake. It is unclear whether tar and nicotine intake from light cigarettes was influenced by vent blocking.
对12名每日吸烟的人研究了通气孔堵塞对一款畅销淡味香烟一氧化碳(CO)暴露的影响。平均CO增加量在以下几种情况之间并无差异:(a)0%滤嘴通气孔堵塞(5.0 ppm),(b)通气孔被嘴唇覆盖(4.9 ppm),(c)50%通气孔被胶带覆盖(4.8 ppm),以及(d)通气孔被指尖捏合覆盖(4.9 ppm)。在另外12名吸烟者中进行了第二项研究,以重复这些发现以及早期的发现,即堵塞通气孔会使1毫克焦油香烟的CO摄入量增加一倍。虽然用手指堵塞一半通气孔显著增加了超淡味香烟的CO增加量(2.8对5.4 ppm,p<0.001),但它并未影响淡味香烟的CO增加量(6.3对6.5 ppm,p = 0.8)。最低焦油含量香烟(1毫克焦油)可能较为特殊。吸烟机模拟对人类吸烟摄入量的模拟效果不佳。尚不清楚淡味香烟的焦油和尼古丁摄入量是否受通气孔堵塞的影响。