Tuffanelli D L
University of California, San Francisco 94108, USA.
Semin Cutan Med Surg. 1998 Mar;17(1):27-33. doi: 10.1016/s1085-5629(98)80059-x.
Localized scleroderma can be divided into three main subtypes: morphea, linear scleroderma, and generalized morphea. Plaque morphea usually has a good prognosis. Variants of morphea, including guttate morphea and atrophoderma of Pasini and Pierini, are seen. Linear scleroderma, whether involving an extremity or the face, is often associated with serological abnormalities. Cosmetic and functional prognosis may be poor. Therapy is usually ineffective. Generalized morphea may be difficult to differentiate from systemic scleroderma. However, progression to systemic scleroderma is uncommon.
硬斑病、线状硬皮病和泛发性硬斑病。斑块状硬斑病通常预后良好。可见硬斑病的变异型，包括点滴状硬斑病以及帕西尼和皮耶里尼萎缩性皮病。线状硬皮病，无论累及肢体还是面部，常伴有血清学异常。外观和功能预后可能较差。治疗通常无效。泛发性硬斑病可能难以与系统性硬皮病相鉴别。然而，进展为系统性硬皮病并不常见。
