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临床经验与晚期HIV及艾滋病女性患者生存情况的关系。

The relationship of clinic experience with advanced HIV and survival of women with AIDS.

作者信息

Laine C, Markson L E, McKee L J, Hauck W W, Fanning T R, Turner B J

机构信息

Center for Research in Medical Education and Health Care, Division of Internal Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

出版信息

AIDS. 1998 Mar 5;12(4):417-24. doi: 10.1097/00002030-199804000-00011.

Abstract

OBJECTIVE

Hospital and physician experience have been linked to improved outcomes for persons with HIV. Because many HIV-infected patients receive care in clinics, we studied clinic HIV experience and survival for women with AIDS.

DESIGN

Retrospective cohort study of women with AIDS whose dominant sources of care were clinics. Clinic HIV experience was estimated as the cumulative number of Medicaid enrollees with advanced HIV who used a particular clinic as their dominant provider up to the year of the patient's AIDS diagnosis: low experience (< 20 patients), medium (20-99 patients), high (> or = 100 patients). Proportional hazards models examined relationships between experience and survival.

SETTING

A total of 117 New York State clinics.

PATIENTS

A total of 887 New York State Medicaid-enrolled women diagnosed with AIDS in 1989-1992.

MAIN OUTCOME MEASURE

Survival after AIDS diagnosis.

RESULTS

In later study years (1991-1992), patients in high experience clinics had an approximately 50% reduction in the relative hazard of death (0.53; 95% confidence interval, 0.35-0.82) compared with patients in low experience clinics. Adjusting for demographic and clinical variables, 71% of patients in high experience clinics were alive 21 months after diagnosis compared with 53% in low experience clinics. Experience and survival were not significantly associated in the early study years (1989-1990).

CONCLUSIONS

In more recent years, women with AIDS receiving care in high experience clinics survived longer after AIDS diagnosis than those in low experience clinics, providing further evidence of a relationship between provider HIV experience and outcomes.

摘要

目的

医院及医生的经验已被证实与改善艾滋病毒感染者的预后有关。由于许多感染艾滋病毒的患者在诊所接受治疗,我们研究了艾滋病女性患者在诊所的艾滋治疗经验与生存情况。

设计

对以诊所为主要治疗来源的艾滋病女性患者进行回顾性队列研究。诊所艾滋治疗经验通过截至患者艾滋病诊断年份,将特定诊所作为主要治疗机构的晚期艾滋医疗补助参保者的累积数量来估算:经验少(<20例患者)、经验中等(20 - 99例患者)、经验丰富(≥100例患者)。比例风险模型用于研究经验与生存之间的关系。

地点

纽约州的117家诊所。

患者

1989 - 1992年纽约州887名诊断为艾滋病的医疗补助参保女性。

主要观察指标

艾滋病诊断后的生存情况。

结果

在随后的研究年份(1991 - 1992年),经验丰富诊所的患者与经验少诊所的患者相比,死亡相对风险降低了约50%(0.53;95%置信区间,0.35 - 0.82)。在对人口统计学和临床变量进行调整后,经验丰富诊所71%的患者在诊断后21个月时仍存活,而经验少诊所这一比例为53%。在早期研究年份(1989 - 1990年),经验与生存之间无显著关联。

结论

近年来,在经验丰富诊所接受治疗的艾滋病女性患者在艾滋病诊断后的存活时间比经验少诊所的患者更长,这进一步证明了医疗服务提供者的艾滋治疗经验与治疗结果之间存在关联。

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