Katz J, Gonzalez B, Cúpula C A, Marini E, Ghiraldo A, Agoff L, Bonilla R, Kersz M, Lucatelli N, Pietrantonio A, Bessaso H, Barcia T, Perisse E, Gentile S, Laferrere L, Jalif A, Georgiev J, Carabajal G, Diaz S M, Pulido M E, Estevez G
Acta Gastroenterol Latinoam. 1997;27(4):253-7.
The aim of this study was to establish the prevalence of H. Pylori infection in patients with chronic gastroduodenal pathology, who were treated in the gastroenterology units of four hospitals located in the Federal Capital and its neighbouring areas. 398 patients were studied by means of clinical assessment and epidemiology data. Upper endoscopy was carried out two biopsies were taken of the gastric antrum for a quick ureasa test and histological assessment of the H. pylori state by means of giemsa's stain. The prevalence of infection on the total of the studied population was 75.6%. In patients with gastric ulcer was 70%; in patients with duodenal ulcer it was 77.2% and 78.5% in patients with chronic gastritis. The prevalence of H. Pylori infection on the population according to age groups was: 61.54% in patients between 21 and 40 years; 76.14% in patients between 41 and 60 years, and 68.22% in patients over 60 year. We have tried to obtain a correlation between the prevalence of the infection and some sanitary characteristic (Running water and sewers) on the studied population. It was seen that 225 patients who lived in dwellings with running water and sewers showed a prevalence of infection of 69.34% and in 129 patients who did not have running water or sewer the rate of prevalence of infection was 83.72; a difference which was statistically significant, (with P < 0.01) for the patients who lived in poor sanitary conditions. These data may be important when the design of therapeutic schemes for the eradication of the bacteria is made.
本研究的目的是确定在联邦首都及其周边地区四家医院的胃肠病科接受治疗的慢性胃十二指肠疾病患者中幽门螺杆菌感染的患病率。通过临床评估和流行病学数据对398名患者进行了研究。进行了上消化道内镜检查，从胃窦取了两块活检组织，用于快速尿素酶试验以及通过吉姆萨染色对幽门螺杆菌状态进行组织学评估。在所研究的总体人群中，感染率为75.6%。胃溃疡患者中的感染率为70%；十二指肠溃疡患者中为77.2%，慢性胃炎患者中为78.5%。根据年龄组划分，人群中幽门螺杆菌感染率为：21至40岁患者中为61.54%；41至60岁患者中为76.14%，60岁以上患者中为68.22%。我们试图在研究人群中找出感染率与一些卫生特征（自来水和下水道）之间的关联。结果发现，居住在有自来水和下水道的住宅中的225名患者，感染率为69.34%，而在没有自来水或下水道的129名患者中，感染率为83.72%；对于生活在卫生条件差的患者，这一差异具有统计学意义（P < 0.01）。在制定根除该细菌的治疗方案时，这些数据可能具有重要意义。
