Myb蛋白在生命、死亡与分化过程中的作用
Myb proteins in life, death and differentiation.
作者信息
Weston K
机构信息
CRC Centre for Cell and Molecular Biology, Chester Beatty Laboratories, London, UK.
出版信息
Curr Opin Genet Dev. 1998 Feb;8(1):76-81. doi: 10.1016/s0959-437x(98)80065-8.
PMID:9529609
Abstract
Myb transcription factors are crucial to the control of proliferation and differentiation in a number of cell types but their mechanism of action is unclear. Regulation of Myb proteins by phosphorylation and intermolecular cooperation has recently been demonstrated, together with a new role for the proteins, in the control of apoptosis.
摘要
Myb转录因子对于多种细胞类型的增殖和分化控制至关重要，但其作用机制尚不清楚。最近已证实通过磷酸化和分子间协作对Myb蛋白进行调控，以及这些蛋白在细胞凋亡控制中的新作用。
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