Sander J E, Resurreccion R S, Waltman W D, McMurray B L
Department of Avian Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602-4875, USA.
Avian Dis. 1998 Jan-Mar;42(1):190-3.
Broiler breeder pullets were vaccinated against fowl cholera at 10 and 20 wk of age using a live PM-1 Pasteurella multocida vaccine administered by wing web stick. Antibody production for P. multocida was measured at vaccination and at 1-4-wk intervals following vaccination by enzyme-linked immunosorbent assay. Groups of vaccinated birds were challenged at 23 and 32 wk of age. Two doses of a live PM-1 P. multocida vaccine protected broiler breeder hens against virulent challenge up to 32 wk of age when measured antibody levels had a range of 1951-4346 and a geometric titer of 3000.
在10周龄和20周龄时，使用通过翼膜刺种接种的活PM-1多杀性巴氏杆菌疫苗对肉种鸡小母鸡进行禽霍乱疫苗接种。在接种疫苗时以及接种后每隔1至4周通过酶联免疫吸附测定法测量多杀性巴氏杆菌的抗体产生情况。对接种疫苗的鸡群在23周龄和32周龄时进行攻毒。当测得的抗体水平范围为1951 - 4346且几何滴度为3000时，两剂量的活PM-1多杀性巴氏杆菌疫苗可保护肉种鸡母鸡直至32周龄免受强毒攻击。
