Mukherjee P K, Saha K, Murugesan T, Mandal S C, Pal M, Saha B P
Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta, India.
J Ethnopharmacol. 1998 Feb;60(1):85-9. doi: 10.1016/s0378-8741(97)00130-x.
Ethanol extract of four different plants of the Khatra region of the Bankura district of West Bengal, India were evaluated for anti-diarrhoeal activity against different experimental models of diarrhoea in rats. The extracts of Ficus bengalensis Linn. (hanging roots), Eugenia jambolana Lam. (bark), Ficus racemosa Linn. (bark) and Leucas lavandulaefolia Rees (aerial parts) showed significant inhibitory activity against castor oil induced diarrhoea and PGE2 induced enteropooling in rats. These extracts also showed a significant reduction in gastrointestinal motility in charcoal meal tests in rats. The results obtained establish the efficacy of all these plant materials as anti-diarrhoeal agents.
对印度西孟加拉邦班库拉区卡特拉地区四种不同植物的乙醇提取物进行了评估，以研究其对大鼠不同腹泻实验模型的抗腹泻活性。孟加拉榕（气生根）、乌墨（树皮）、聚果榕（树皮）和薰衣草叶香科科（地上部分）的提取物对蓖麻油诱导的大鼠腹泻和前列腺素E2诱导的大鼠肠积液显示出显著的抑制活性。这些提取物在大鼠炭末推进试验中也显示出胃肠道蠕动显著降低。所获得的结果证实了所有这些植物材料作为抗腹泻剂的有效性。
