de Jong N W, Vermeulen A M, Gerth van Wijk R, de Groot H
Department of Allergology, University Hospital Dijkzigt, Rotterdam, The Netherlands.
Allergy. 1998 Feb;53(2):204-9. doi: 10.1111/j.1398-9995.1998.tb03872.x.
We describe 14 consecutive patients with complaints due to the handling of flowers. The symptoms varied from allergic rhinoconjunctivitis and asthma to urticaria. Most patients had professions in the flower industry. Skin prick tests (SPT) were performed with home-made pollen extracts from 17 different flowers known to be the most commonly grown and sold in The Netherlands RAST against mugwort, chrysanthemum, and solidago was performed. The diagnosis of atopy against flowers was based on work-related symptoms due to the handling of flowers, positive SPT with flower extracts, and positive RAST. The concordance between SPT and case history was 74%, and that between SPT and RAST was 77% Extensive cross-sensitization was seen to pollen of several members of the Compositae family (e.g., Matricaria, chrysanthemum, solidago) and to pollen of the Amaryllidaceae family (Alstroemeria and Narcissus). Homemade flower extracts can be used to confirm IgE-mediated flower allergy. Mugwort can be used as a screening test for possible flower allergy. For most patients, the allergy led to a change of profession.
我们描述了14例因接触花卉而出现不适症状的连续病例。症状从过敏性鼻结膜炎、哮喘到荨麻疹不等。大多数患者从事花卉行业。我们用从荷兰最常见种植和销售的17种不同花卉自制的花粉提取物进行了皮肤点刺试验(SPT),并针对艾蒿、菊花和一枝黄花进行了放射性变应原吸附试验(RAST)。对花卉过敏的诊断基于接触花卉引起的与工作相关的症状、花卉提取物皮肤点刺试验阳性以及放射性变应原吸附试验阳性。皮肤点刺试验与病史之间的一致性为74%,皮肤点刺试验与放射性变应原吸附试验之间的一致性为77%。观察到对菊科几个成员(如母菊、菊花、一枝黄花)的花粉以及对石蒜科(六出花和水仙)的花粉有广泛的交叉致敏。自制的花卉提取物可用于确认IgE介导的花卉过敏。艾蒿可作为可能的花卉过敏的筛查试验。对大多数患者来说,过敏导致了职业的改变。