Suwanchaichinda C, Paskewitz S M
Department of Entomology, University of Wisconsin-Madison 53706, USA.
J Med Entomol. 1998 Mar;35(2):157-61. doi: 10.1093/jmedent/35.2.157.
A Plasmodium-refractory strain (L35) of the mosquito Anopheles gambiae Giles melanizes late ookinetes on the basal surface of the midgut, resulting in the death of the parasites. This strain also melanizes CM C-25 Sephadex beads, which serve as a model system for investigating the melanization response. The effects of larval nutrition, adult body size, and temperature of the adult environment on the ability of refractory females to melanize CM C-25 beads were studied. Nutritional deprivation during the larval stages significantly decreased the ability of adults to melanize beads. In addition, bead melanization decreased progressively as the environmental temperature of the adults increased from 24 to 30 degrees C. We conclude that environmental stress may affect the immune responses of An. gambiae.
冈比亚按蚊（Anopheles gambiae Giles）的一个对疟原虫具有抗性的品系（L35）会使中肠基底面的晚期动合子黑化，从而导致寄生虫死亡。该品系还会使CM C - 25葡聚糖凝胶珠黑化，后者作为研究黑化反应的模型系统。研究了幼虫营养、成虫体型和成虫环境温度对抗性雌蚊黑化CM C - 25珠能力的影响。幼虫阶段的营养剥夺显著降低了成虫黑化珠子的能力。此外，随着成虫环境温度从24℃升高到30℃，珠子黑化程度逐渐降低。我们得出结论，环境压力可能会影响冈比亚按蚊的免疫反应。
