Ryan M E, Geenen J E, Lehman G A, Aliperti G, Freeman M L, Silverman W B, Mayeux G P, Frakes J T, Parker H W, Yakshe P N, Goff J S
Department of Gastroenterology, Marshfield Clinic, Wis 54449, USA.
Gastrointest Endosc. 1998 Mar;47(3):261-6. doi: 10.1016/s0016-5107(98)70324-4.
Endoscopic therapy of biliary tract leaks was uncommon before laparoscopic cholecystectomy. Studies have demonstrated the efficacy of endoscopic drainage by endoscopic sphincterotomy or stent placement. Various endoscopic therapeutic modalities and long-term follow-up of this problem were studied.
Members of the Midwest Pancreaticobiliary Group reviewed all patients referred for endoscopic therapy of biliary leaks after laparoscopic cholecystectomy from 1990 to 1994. Long-term follow-up was by direct patient contact.
Fifty patients were referred for endoscopic therapy of biliary leaks. Abdominal pain was present in 94%. The mean time from laparoscopic cholecystectomy to referral was 6.9 days. Therapy consisted of sphincterotomy only in 6 patients, stent only in 13, and sphincterotomy with stent in 31. Biliary leaks were healed in 44 patients at a mean of 5.4 weeks. A second or third endoscopic procedure was necessary to achieve healing in five patients. Two stent-related complications were noted. Percutaneous or surgical drainage of biliary fluid collections was required in 16 patients. The mean hospital stay for treatment of the leak was 11.1 days after endoscopic therapy. On follow-up (mean 17.5 months), all patients were well except two with mild abdominal discomfort.
Endoscopic sphincterotomy, stent placement, or sphincterotomy with stent are effective in healing biliary leaks after laparoscopic cholecystectomy. Despite prolonged treatment for the leak, patients did well on long-term follow-up.
在腹腔镜胆囊切除术出现之前,内镜治疗胆道漏并不常见。研究已证实内镜括约肌切开术或支架置入术进行内镜引流的有效性。对该问题的各种内镜治疗方式及长期随访情况进行了研究。
中西部胰胆疾病研究小组的成员回顾了1990年至1994年因腹腔镜胆囊切除术后胆道漏而接受内镜治疗的所有患者。通过直接与患者联系进行长期随访。
50例患者因胆道漏接受内镜治疗。94%的患者存在腹痛。从腹腔镜胆囊切除术到转诊的平均时间为6.9天。治疗方式包括仅行括约肌切开术的6例患者,仅置入支架的13例患者,以及行括约肌切开术加支架置入术的31例患者。44例患者的胆道漏在平均5.4周时愈合。5例患者需要进行第二次或第三次内镜操作才能实现愈合。记录到2例与支架相关的并发症。16例患者需要经皮或手术引流胆汁积聚。内镜治疗后,治疗漏的平均住院时间为11.1天。在随访(平均17.5个月)时,除2例有轻度腹部不适外,所有患者情况良好。
内镜括约肌切开术、支架置入术或括约肌切开术加支架置入术对腹腔镜胆囊切除术后的胆道漏愈合有效。尽管对漏的治疗时间较长,但患者在长期随访中情况良好。